Characteristics of a large mumps outbreak: Clinical severity, complications and association with vaccination status of mumps outbreak cases

Figures & data

Table 1. General characteristics of mumps cases in the Jerusalem district during September 2009 – August 2011 (n=3130)

Characteristic	N (%)
Age groups (years)
<1	23 (0.7%)
1–4	363 (11.6%)
5–9	626 (20%)
10–14	895 (28.6%)
15–19	540 (17.3%)
20–24	284 (9.1%)
25–29	155 (5%)
30+	244 (7.8%)
Male gender (%)	1998 (63.8%)
Year of the outbreak
2009	523 (16.7%)
2010	2,488 (79.5%)
2011	119 (3.8%)
Vaccination status: Number of mumps vaccine doses
0	775 (24.8%)
1	886 (28.3%)
2	1,469 (46.9%)
Locus of medical care
Hospital	79 (2.5%)
Emergency care center	340 (10.9%)
Community clinic	2,711 (86.6%)
Attended an educational facility	2,291 (73.2%)
>1 mumps case in the household	876 (28%)

Figure 1. The mumps vaccination status of patients with outbreak-associated mumps in the Jerusalem district (September 6th 2009 - August 12th 2011), according to the age of the patients and the number of doses of measles–mumps–rubella (MMR) vaccine received before the outbreak.

Table 2. Association between mumps complications, hospitalization and MMR vaccination status, mumps cases in the Jerusalem district during September 2009 – August 2011 (n = 3,130)

complication	No. MMR Vaccine doses received	No cases with complications /total (%)	Adjusted Odds Ratio (95%CI)	p value	Adjusted Vaccine Effectiveness (95% CI)
Hospitalization	0	163/775(21)	Ref	Ref	Ref
	1	107/886 (12.1)	0.72 (0.53–0.97)	0.03	28 (3.1–46.5)
	2	149/1,496 (10.1)	0.56 (0.43–0.73)	0.0001	43.7 (26.9–56.6)
Orchitis	0	26/336 (7.7)	Ref	Ref	Ref
	1	7/194 (3.6)	0.51 (0.21–1.24)	0.13	49.3 (−24.3–79.4)
	2	9/579 (1.6)	0.2 (0.095–0.55)	0.001	77.1 (45–90.5)
Meningitis	0	6/775 (0.8)	Ref	Ref	Ref
	1	2/886 (0.2)	0.26 (0.05–1.4)	0.12	74 (−44–95.3)
	2	7/1,469 (0.5)	0.56 (0.17–1.8)	0.34	43.5 (−82 −82.4)
All complications	0	30/775 (3.9)	Ref	Ref	Ref
	1	11/886 (1.2)	0.48 (0.22–1.04)	0.063	52.1 (−4 −78)
	2	16/1,469 (1.1)	0.37 (0.19–0.74)	0.005	62.7 (25.7–81.3)

* Adjusted for age (as continuous variable) and gender expect orchitis which was adjusted only for age among males>12 years.