Serotype distribution of Streptococcus pneumoniae in children with invasive diseases in Turkey: 2008–2014

Figures & data

Table 1. The site of infection according to the years

	Study period
	2008–2010	2011–2012	2013–2014
The site of infection	n (%)	n (%)	n (%)
Bacteremia/sepsis	100 (49.5)	33 (49.2)	37 (56.0)
Meningitis	63 (31.2)	26 (38.8)	18 (27.3)
Empyema	39 (19.3)	8 (12.0)	11 (16.7)

Table 2. Serotype distribution of Streptococcus pneumoniae according to age groups per year in Turkey

Study period (year)	2008–2010		2011–2012		2013–2014		2008–2014
Age Groups	≤5 yr	≤5- ≤18 yr	≤5 yr	>5- ≤18 yr	≤5 yr	>5- ≤18 yr	≤5 yr	>5- ≤18 yr
Serotypes	n	n	n	n	n	n	n	n
PCV-7 serotypes
4	11	3	1	0	2	0	14	3
6B	14	2	3	0	1	0	18	2
9V	1	1	2	2	1	1	4	4
14	10	2	2	0	1	5	13	7
18C	4	1	0	1	0	0	4	2
19F	36	3	3	4	7	0	46	7
23F	8	0	4	0	2	0	14	0
PCV-10 additional serotypes
1	6	2	0	1	1	1	7	4
5	4	0	1	1	1	2	6	3
7F	1	0	0	0	1	2	2	2
PCV-13 additional serotypes
3	6	4	3	2	5	0	14	6
6A	3	2	0	4	0	1	3	7
19A	9	1	3	1	1	1	13	3
Non-PCV-13 serotypes
2	2	0	0	0	1	0	3	0
6	0	1	0	0	0	0	0	1
7A	1	4	0	0	0	0	1	4
8	2	3	0	1	1	1	3	5
10	1	1	0	1	0	1	1	3
15	2	3	0	2	0	0	2	5
15C	2	3	1	2	0	1	3	6
16F	1	0	0	0	0	0	1	0
17	0	1	0	0	0	0	0	1
23A	1	0	1	1	0	0	2	1
Other^*	15	12	7	11	9	9	31	32
Not determined	6	7	0	2	4	3	10	12
Total number of evalvated clinacal samples	146	56	31	36	38	28	215	120

* Including 15B, 20, G+, D+, R+, etc.

Figure 1. Vaccine serotype coverage rates for PCV-7, PCV-10 and PCV-13 before and after inclusion of PCV-7 and PCV-13 in Turkey's NIP according to the years.

Figure 2. CONSORT flow diagram showing number of IPD cases enrolled in the study, study periods and vaccination status of the IPD cases according to the years.