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Research Paper

Safety and immunogenicity of a Herpes Zoster subunit vaccine in Japanese population aged ≥50 years when administered subcutaneously vs. intramuscularly

, , , , , & show all
Pages 574-578 | Received 28 Jun 2016, Accepted 01 Sep 2016, Published online: 23 Dec 2016

Figures & data

Figure 1. Disposition of study participants. SC: Subcutaneous IM: Intramuscular.

Figure 1. Disposition of study participants. SC: Subcutaneous IM: Intramuscular.

Figure 2. Vaccine response rate and geometric mean concentrations of anti-gE antibody (ATP cohort for immunogenicity). Samples were collected at the indicated time points (for both subcutaneous (SC) versus intramuscular (IM) groups) and anti-gE antibody concentrations were determined by ELISA. Data are vaccine response rates (VRRs) and geometric mean concentrations (GMCs) and error bars indicate 95% confidence interval.

Figure 2. Vaccine response rate and geometric mean concentrations of anti-gE antibody (ATP cohort for immunogenicity). Samples were collected at the indicated time points (for both subcutaneous (SC) versus intramuscular (IM) groups) and anti-gE antibody concentrations were determined by ELISA. Data are vaccine response rates (VRRs) and geometric mean concentrations (GMCs) and error bars indicate 95% confidence interval.

Figure 3. Overall occurrence of solicited injection site reactions and general symptoms during the 7-day vaccination follow-up period (Total vaccinated cohort).

Figure 3. Overall occurrence of solicited injection site reactions and general symptoms during the 7-day vaccination follow-up period (Total vaccinated cohort).