Determinants of influenza vaccination among solid organ transplant recipients attending Sicilian reference center

Figures & data

Table 1. Demographics and clinical characteristics of SOT recipients attending RC during 2014–2015 influenza season.

		Total N	Vaccinated against influenza (n = 31),	Unvaccinated against influenza (n = 51),
		(%-IQR)	N (%-IQR)	N (%-IQR)	p
Sex	Male	60 (73.2)	26 (43.3)	34 (56.7)	0.088
	Female	22 (26.8)	5 (22.7)	17 (77.3)
Age		49.8 (46.6–52.0)	53.6 (48.6–50.5)	47.5 (43.4–51.6)	0.063
Country of origin	Italian	79 (96.3)	31 (39.2)	48 (70.8)	0.169
	Other	3 (3.7)	0 (0)	3 (100)
School level	Nothing	3 (3.7)	2 (66.4)	1 (33.3)	0.128
	Primary	23 (28.0)	11 (47.8)	12 (52.2)
	Secondary	27 (32.9)	12 (44.4)	15 (55.6)
	College	19 (23.2)	3 (15.8)	16 (84.2)
	University	10 (12.2)	3 (30.0)	7 (70.0)
Employment status	Employed	40 (48.8)	8 (20.0)	32 (80.0)	0.004
	Retired	31 (37.8)	18 (58.1)	13 (41.9)
	Unemployed	11 (13.4)	5 (45.5)	6 (54.5)
Smoking habits	Never	43 (52.4)	12 (27.9)	31 (71.1)	0.132
	Not for 10 y	16 (19.6)	7 (43.7)	9 (56.3)
	Yes	23 (28.0)	12 (52.2)	11 (47.8)
ILI for 3 last seasons	Yes	35 (42.7)	8 (22.8)	27 (77.2)	0.016
Source of information about influenza vaccination	General Practitioner	29 (35.4)	12 (41.4)	17 (58.6)	0.022
	Reference center physician	19 (23.2)	16 (84.2)	3 (15.8)
	Parents/friends	4 (4.9)	2 (50.0)	2 (50.0)
	Other physician	5 (6.1)	1 (20.0)	4 (80.0)
Vaccination against pneumococcus	Yes	17 (20.7)	11 (64.7)	6 (35.3)	0.010
Performed transplant	Liver	34 (41.5)	13 (38.2)	21 (61.8)	0.653
	Heart	9 (11.0)	4 (44.4)	5 (55.6)
	Heart and kidney	1 (1.2)	0 (0)	1 (100)
	Lung	22 (26.8)	9 (40.9)	13 (59.1)
	Kidney	15 (18.3)	4 (26.7)	11 (73.3)
	Liver and kidney	1 (1.2)	1 (100)	0 (0)
Medical history	Bronchopulmunary diseases	26 (31.7)	13 (50.0)	13 (50.0)	0.121
	Cardiovascular diseases	60 (73.2)	24 (40.0)	36 (60.0)	0.498
	Diabetes	25 (30.5)	10 (40.0)	15 (60.0)	0.786
	Chronical renal failure	25 (30.5)	8 (32.0)	17 (68.0)	0.473
	Immunosuppressive diseases	1 (1.2)	0 (0)	1 (100)	0.433
	Chronic hepatitis	31 (37.8)	12 (38.7)	19 (61.3)	0.895
	Leukemia/lymphoma	3 (3.7)	0 (0)	3 (100)	0.169
	Solid tumor	9 (11.0)	4 (44.4)	5 (55.6)	0.663
	Other diseases	51 (62.2)	18 (35.3)	33 (64.7)	0.548

Table 2. Multivariate analysis of factors associated with influenza vaccine uptake among SOT recipients during 2014–2015 influenza season.

	OR	95% CI
Sex (Male Vs. Female)	2.5	0.5	12.0
Age (per year increase)	1.0	0.9	1.1
Worker (Yes Vs. No)	0.4	0.1	2.5
Retired (Yes Vs. No)	1.3	0.1	11.8
ILI for 3 previous seasons (Yes Vs. No)	0.4	0.1	1.3
Vaccination against pneumococcus (Yes Vs. No)	7.0	1.4	34.4
Influenza vaccination information by Reference Center physician (Yes Vs. No)	53.4	7.2	394.8
Influenza vaccination information by General Practitioner (Yes Vs. No)	4.6	0.9	22.9

Figure 1. Reasons for missed vaccination in SOT recipients.

Figure 2. Following hospitalizations for respiratory disease among SOT recipients with or without performing anti-influenza vaccine during 2014–2015 influenza season.