Hospitalizations for pneumonia, invasive diseases and otitis in Tuscany (Italy), 2002-2014: Which was the impact of universal pneumococcal pediatric vaccination?

Figures & data

Figure 1. Number of hospitalizations and hospitalization rate (x 100,000 inhabitants) potentially due to pneumococcal diseases in Tuscany (2002–2014).

Figure 2. Average annual rates of hospitalization potentially due to pneumococcal diseases, by age group, in PVP (2002–2007) and VP (2009–2014) in Tuscany.

Table 1. Type of hospitalization, gender and citizenship of hospitalized subjects in Tuscany, in PVP (2002–2007) and VP (2009–2014).

HOSPITALIZATIONS		PVP (2002–2007) N° (%)	VP (2009–2014) N° (%)
GENDER	MALES	65,165 (51.0%)	85,074 (50.6%)
	FEMALES	62,491 (49.0%)	82,861 (49.3%)
TYPE	ORDINARY	145,311 (94.7%)	162,991 (97.0%)
	DAY-HOSPITAL	8,083 (5.3%)	5,060 (3.0%)
CITIZENSHIP	ITALIAN	148,844 (97.0%)	161,292 (96.0%)
	FOREIGN	3,245 (2.1%)	4,862 (2.9%)
	UNKNOWN	1,305 (0.9%)	1,897 (1.1%)

Table 2. ICD-9-CM diagnosis codes of potentially associated S. pneumoniae diseases selected for the analysis.

DIAGNOSIS	CODE	DIAGNOSIS	Code
Septicemia	38	Bacterial infection in conditions classified elsewhere and of unspecified site	041.0
Streptococcal septicemia	038.0	Pneumococcal infection in conditions classified elsewhere	041.2
Pneumococcal septicemia	038.2	Acute pericarditis	420
Unspecified septicemia	038.9	Acute pericarditis	420.0
Bacteremia NOS	790.7	Acute pericarditis in conditions classified elsewhere	420.9
Suppurative and unspecified otitis media	382	Acute pericarditis, unspecified	420.90
Acute suppurative otitis media	382.0	Acute idiopathic pericarditis	420.91
Unspecified otitis media	382.9	Other pericarditis	420.99
Bacterial meningitis	320	Acute myocarditis	422
Pneumococcal meningitis	320.1	Acute myocarditis in diseases classified elsewhere	422.0
Streptococcal meningitis	320.2	Other and unspecified acute myocarditis	422.9
Meningitis in other bacterial diseases classified elsewhere	320.7	Acute myocarditis, unspecified	422.90
Meningitis due to other specified bacteria	320.8	Idiopathic myocarditis	422.91
Meningitis due to unspecified bacterium	320.9	Septic myocarditis	422.92
Meningitis of unspecified cause	322	Pleurisy without mention of effusion or current tuberculosis	511.0
Meningitis, unspecified	322.9	Pleurisy with effusion, with mention of a bacterial cause other than tuberculosis	511.1
Acute bronchitis	466.0	Pneumococcal peritonitis	567.1
Viral pneumonia	480	Urinary tract infection, site not specified	599.0
Pneumococcal pneumonia	481	Pyogenic arthritis (included pneumococcal arthritis)	711.0
Other bacterial pneumonia	482	Bronchopneumonia, organism unspecified	485
Pneumonia due to other specified organism	483	Pneumonia, organism unspecified	486
Pneumonia in infectious diseases classified elsewhere	484	Influenza with pneumonia	487.0

Figure 3. Total days of hospitalization potentially due to pneumococcal diseases in Tuscany, by age, in PVP (2002–2007) and VP (2009–2014).

Figure 4. Total cost of hospitalization potentially due to pneumococcal diseases in Tuscany, by age group, in PVP (2002–2007) and VP (2009–2014).