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Research Papers

Vaccines for epidemic infections and the role of CEPI

Pages 2755-2762 | Received 14 Feb 2017, Accepted 10 Mar 2017, Published online: 27 Apr 2017

Figures & data

Table 1. Pathogens for which vaccines are needed selected by various organizations.

Table 2. Stages of development supported by CEPI.

Table 3. Prioritization of pathogens by different groups.

Table 4. Platforms that might be made constantly available for unforeseen epidemics.

Table 5. Chikungunya candidate vaccines.

Table 6. Viruses isolated from bats (selected).

Table 7. The five stages through which pathogens of animals evolve to cause diseases confined to humans. Virtually all animal-derived human pathogens arose from pathogens of other warm-blooded vertebrates, primarily mammals plus in two cases (influenza A and ultimately falciparum malaria) birds. Primates constitute only 0.5% of all vertebrate species but have contributed about 20% of our major human diseases. (Adapted from Ref. Citation62.)

Table 8. Virus traits potentially relevant for capacity to emerge and cause disease in human populations (modified from Ref. Citation65).

Table 9. Viruses (n = 37) that are known or suspected of being transmissible (directly or indirectly) between humans but to date have been restricted to short transmission chains or self-limiting outbreaks (modified from Ref. Citation65).

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