Figures & data
Figure 1. Schema for factorial design with two interventional factors, immune ablation and anti-PD1 antibody administration.
Figure 2A. Two-stage phase II/III design; Selection design for selecting among three test regimens followed by phase III design of the selected regimen compared to a standard control regimen.
Figure 2B. Two stage phase II/III design; Phase II selection design comparing two test regiment and control followed by phase III design of one of the selected regimens and the control. The phase II data can be used in the final analysis because the control appears in both phase II and phase III portions.
