Influenza vaccines: Evaluation of the safety profile

Figures & data

Table 1. Vaccine types and route of administration.

Vaccine types	Route of administration
TIV	Parenteral Intradermal
QIV	Parenteral
LAIV	Intranasally

Table 2. Most common local and systemic reactions in children.

Children
Vaccine	Local reaction		Systemic Reaction
TIV	Pain		Irritability
	Redness		Malaise
	Tenderness		Headache
adjuvanted TIV	Pain		Irritability
	Tenderness
			Diarrhea
	Erythema
			Crying
	Induration
			Fatigue
			Chills
			Headache
			Fever
			Myalgia
LAIV	Nasal congestion		Fever
			Decreased activity
Pandemic	Pain		Malaise
	Redness		Fatigue
	Swelling		Myalgia

Table 3. Most common local and systemic reactions in adults and the elderly.

Adult - Elderly
Vaccine	Local reaction	Systemic Reaction
TIV/QIV	Pain	Fatigue
adjuvanted-non		Myalgia
adjuvanted		Headache
LAIV	Cough	Decreased appetite
	Sore throat
	Runny rose/nasal congestion
Pandemic	Pain	Fever
		Headache
		Malaise
		Fatigue
		Myalgia

Table 4. Most common local and systemic reactions in high-risk individuals.

High-risk individuals
Vaccine	Local reaction	Systemic Reaction
TIV	Pain	Myalaise
		Myalgia
Pandemic	Pain	Fatigue
	Tenderness	Decreased activity