Time-dependent changes of the intention of mothers in Japan to inoculate their daughters with the HPV vaccine after suspension of governmental recommendation

Figures & data

Table 1. Characteristics of the internet survey responders.

		1^st (Mar. 2014)		2^nd (May. 2015)		3^rd (Feb. 2016)
Mothers with unvaccinated daughter		Number	Percent	Number	Percent	Number	Percent
Total		200	100.0%	2060	100.0%	2000	100.0%
Age	30-39	80	40.0%	488	23.7%	273	13.7%
	40–49	116	58.0%	1449	70.3%	1491	74.6%
	50–59	4	2.0%	119	5.8%	235	11.8%
	60-	0	0%	4	0.2%	1	0.1%
Residence area	Hokkaido/ Tohoku	23	11.5%	235	11.4%	218	10.9%
	Kanto	77	38.5%	714	34.7%	696	34.8%
	Chubu/Kinki	62	31.0%	754	36.6%	808	40.4%
	Chugoku/Shikoku	19	9.5%	157	7.6%	138	6.9%
	Kyusyu	19	9.5%	200	9.7%	140	7.0%
Education	Junior/Senior high-school	59	29.5%	712	34.6%	614	30.7%
	Junior/Technical college	84	42.0%	846	41.0%	838	41.9%
	University/Graduate school	57	28.5%	498	24.2%	545	27.3%
	Other	0	0%	4	0.2%	3	0.2%

Table 2. Intention for inoculation: Vaccinate without any specific conditions under suspension of active recommendation.

	Inoculate		Unsure	Won't inoculate
1^st (Mar. 2014)	35	(17.5%)^*1	165	(82.5%)
			114 (57.0%)	51 (25.5%)
2^nd (May. 2015)	250	(12.1%)^*1^*2	1810	(87.9%)
			977 (47.4%)	833 (40.4%)
3^rd (Feb. 2016)	133	(6.7%)^*2^*3	1867	(93.4%)
			986 (49.3%)	881 (44.1%)

*¹ p = 0.03 (Fisher's exact test).

*² p < 0.01 (Fisher's exact test).

*³ p < 0.01 (Fisher's exact test) (compared to *6 in Table 3).

Table 3. Intention of inoculation: Vaccinate after restart of the recommendation.

	Inoculate		Unsure	Won't inoculate
1^st (Mar. 2014)	45	(22.5%)^*2	155	(77.5%)
			118 (59.0%)	37 (18.5%)
2^nd (May. 2015)	433	(21.0%)^*5^*6	1627	(79.0%)
			1118 (54.3%)	509 (24.7%)
3^rd (Feb. 2016)	244	(12.2%)^*5^*6	1756	(87.8%)
			1106 (55.3%)	650 (32.5%)

*² p = 0.65 (Fisher's exact test).

*⁵ p < 0.01 (Fisher's exact test).

*⁶ p < 0.01 (Fisher's exact test) (compared to *3 in Table 2).

Table 4. Vaccinate after restart of the recommendation (After reading messages).

	Inoculate		Unsure	Won't inoculate
1^st (Mar. 2014)	47	(23.5%)^*7	153	(76.5%)
			113 (56.5%)	40 (20.0%)
2^nd (May. 2015)	562	(27.3%)^*7^*8	1498	(72.7%)
			1071 (52.0%)	427 (20.7%)
3^rd (Feb. 2016)	497	(24.9%)^*8^*9	1503	(75.2%)
			1086 (54.3%)	417 (20.9%)

*⁷ p = 0.28 (Fisher's exact test).

*⁸ p = 0.08 (Fisher's exact test).

*⁹ p < 0.01 (Fisher's exact test) (compared to *6 in Table 3).

Figure 1. Survey for the mothers’ intentions towards HPV vaccination for daughters.