2,568
Views
9
CrossRef citations to date
0
Altmetric
Research Paper

Antibody persistence in pre-school children after hexavalent vaccine infant primary and booster administration

, , , , , & show all
Pages 658-668 | Received 16 Aug 2018, Accepted 28 Oct 2018, Published online: 31 Jan 2019

Figures & data

Figure 1. Participant disposition. Primary series and booster data from Madhi et al (Study 1, South Africa)Citation16,Citation24 and Lopez et al (Study 2, Colombia) Citation20.

*, coadministered with MMR-V; †, coadministered with PCV7 (2, 4, 6 months) and rotavirus vaccine (2, 4 months); ‡, coadministered with PCV7 and MMR-V; #, data only available for Colombia at 3.5 years and 4.5 years of age in Study 2 (due to closure of site in Costa Rica)

Figure 1. Participant disposition. Primary series and booster data from Madhi et al (Study 1, South Africa)Citation16,Citation24 and Lopez et al (Study 2, Colombia) Citation20.*, coadministered with MMR-V; †, coadministered with PCV7 (2, 4, 6 months) and rotavirus vaccine (2, 4 months); ‡, coadministered with PCV7 and MMR-V; #, data only available for Colombia at 3.5 years and 4.5 years of age in Study 2 (due to closure of site in Costa Rica)

Table 1. Anti-hepatitis B antibody response post-primary vaccination, pre- and post-booster in second year of life, and persistence at 3.5 and 4.5 years of age.

Table 2. Anti-diphtheria antibody response post-primary vaccination, pre- and post-booster in second year of life, and persistence at 3.5 and 4.5 years of age.

Table 3. Anti-tetanus antibody response post-primary vaccination, pre- and post-booster in second year of life, and persistence at 3.5 and 4.5 years of age.

Table 4. Anti-poliovirus 1, 2, and 3 antibody response post-primary vaccination, pre- and post-booster in second year of life, and persistence at 3.5 and 4.5 years of age.

Table 5. Anti-pertussis (anti-PT and anti-FHA) antibody geometric mean concentrations post-primary vaccination, pre- and post-booster in second year of life, and persistence at 3.5 and 4.5 years of age.

Table 6. Anti-PRP antibody response post-primary vaccination, pre- and post-booster in second year of life, and persistence at 3.5 and 4.5 years of age.