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Research Paper

Comparison of anti-HBs persistence after hepatitis B vaccination on two-dose schedule and three-dose schedule among adults: results from a 12-year follow up study in China

Jingjing LuSchool of Public Health, Shandong University, Ji’nan, China;Shandong Provincial Key Laboratory of Infectious Disease Control and Prevention, Shandong Provincial Center for Disease Control and Prevention, Ji’nan, ChinaCorrespondence[email protected]
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Bingyu YanSchool of Public Health, Shandong University, Ji’nan, China;Shandong Provincial Key Laboratory of Infectious Disease Control and Prevention, Shandong Provincial Center for Disease Control and Prevention, Ji’nan, ChinaView further author information

Jiaye LiuSchool of Public Health, Shandong University, Ji’nan, China;Shandong Provincial Key Laboratory of Infectious Disease Control and Prevention, Shandong Provincial Center for Disease Control and Prevention, Ji’nan, ChinaView further author information

Wenlong WuSchool of Public Health, Shandong University, Ji’nan, China;Shandong Provincial Key Laboratory of Infectious Disease Control and Prevention, Shandong Provincial Center for Disease Control and Prevention, Ji’nan, ChinaView further author information

Yi FengSchool of Public Health, Shandong University, Ji’nan, China;Shandong Provincial Key Laboratory of Infectious Disease Control and Prevention, Shandong Provincial Center for Disease Control and Prevention, Ji’nan, ChinaView further author information

Aiqiang XuSchool of Public Health, Shandong University, Ji’nan, China;Shandong Provincial Key Laboratory of Infectious Disease Control and Prevention, Shandong Provincial Center for Disease Control and Prevention, Ji’nan, ChinaCorrespondence[email protected]
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Li ZhangSchool of Public Health, Shandong University, Ji’nan, China;Shandong Provincial Key Laboratory of Infectious Disease Control and Prevention, Shandong Provincial Center for Disease Control and Prevention, Ji’nan, ChinaView further author information

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Figures & data

Table 1. The characteristic of study population between completed follow-up and not complete follow-up.

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Table 2. Percentage of subjects with anti-HBs titers 0–9, 10–99, 100–999 and ≥1000 mIU/mL and GMC at twelve years after the primary series, stratified by immunization schedule.

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Figure 1. Study design and disposition of subjects.

Figure 2. Reverse cumulative distribution curves of anti-HBs titres at 12 years.

Table 3. Multivariable model analysis on seroprotection rate (≥10 mIU/ml) and GMC at twelve years after HepB-SC primary immunization.

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Comparison of anti-HBs persistence after hepatitis B vaccination on two-dose schedule and three-dose schedule among adults: results from a 12-year follow up study in China

Table 1. The characteristic of study population between completed follow-up and not complete follow-up.

Table 2. Percentage of subjects with anti-HBs titers 0–9, 10–99, 100–999 and ≥1000 mIU/mL and GMC at twelve years after the primary series, stratified by immunization schedule.

Table 3. Multivariable model analysis on seroprotection rate (≥10 mIU/ml) and GMC at twelve years after HepB-SC primary immunization.

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Comparison of anti-HBs persistence after hepatitis B vaccination on two-dose schedule and three-dose schedule among adults: results from a 12-year follow up study in China

Figures & data

Table 1. The characteristic of study population between completed follow-up and not complete follow-up.

Table 2. Percentage of subjects with anti-HBs titers 0–9, 10–99, 100–999 and ≥1000 mIU/mL and GMC at twelve years after the primary series, stratified by immunization schedule.

Table 3. Multivariable model analysis on seroprotection rate (≥10 mIU/ml) and GMC at twelve years after HepB-SC primary immunization.

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Academic Permissions

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