Questionnaire survey on maternal pertussis vaccination for pregnant women and mothers in Nara prefecture, Japan

Figures & data

Table 1. Maternal Tdap vaccination questionnaire (n, %).

1. Before reading the information, did you know that whooping cough can be prevented by vaccination?
	Yes	No	Unsure	No answer	P-value
Ob/Gyn	90 (18.7%)	392 (81.3%)	0 (0.0%)	0 (0.0%)	0.007
Pediatrics	120 (26.0%)	340 (73.8%)	0 (0.0%)	1 (0.2%)
Total	210 (22.2%)	732 (77.6%)	0 (0.0%)	1 (0.1%)
2. Before reading the information, did you know that infantile whooping cough can be very severe and life-threatening?
	Yes	No	Unsure	No answer	P-value
Ob/Gyn	89 (18.5%)	393 (81.5%)	0 (0.0%)	0 (0.0%)	<0.001
Pediatrics	131 (28.4%)	329 (71.4%)	0 (0.0%)	1 (0.2%)
Total	220 (23.3%)	722 (76.6%)	0 (0.0%)	1 (0.1%)
3. Before reading the information, did you know that infantile whooping cough can be prevented by vaccination for pregnant women?
	Yes	No	Unsure	No answer	P-value
Ob/Gyn	19 (3.9%)	463 (96.1%)	0 (0.0%)	0 (0.0%)	0.352
Pediatrics	24 (5.2%)	436 (94.6%)	0 (0.0%)	1 (0.2%)
Total	43 (4.6%)	899 (95.3%)	0 (0.0%)	1 (0.1%)
4. After reading the information, do you hope that Tdap vaccine will be approved in Japan?
	Yes	No	Unsure	No answer	P-value
Ob/Gyn	450 (93.4%)	26 (5.4%)	3 (0.6%)	3 (0.6%)	0.658
Pediatrics	427 (92.6%)	25 (5.4%)	3 (0.7%)	6 (1.3%)
Total	877 (93.0%)	51 (5.4%)	6 (0.6%)	9 (1.0%)
5. After reading the information, do you hope that maternal Tdap vaccine will be included in the NIP?
	Yes	No	Unsure	No answer	P-value
Ob/Gyn	449 (93.2%)	25 (5.2%)	4 (0.8%)	4 (0.8%)	0.490
Pediatrics	424 (92.0%)	29 (6.3%)	2 (0.4%)	6 (1.3%)
Total	873 (92.6%)	54 (5.7%)	6 (0.6%)	10 (1.1%)
6. After reading the information, would you have the maternal Tdap vaccine in the case of voluntary vaccination (you need to pay)?
	Yes	No	Unsure	No answer	P-value
Ob/Gyn	326 (67.6%)	139 (28.8%)	13 (2.7%)	4 (0.8%)	0.955
Pediatrics	311 (67.5%)	135 (29.3%)	9 (2.0%)	6 (1.3%)
Total	637 (67.6%)	274 (29.1%)	22 (2.3%)	10 (1.1%)
7. After reading the information, would you have the maternal Tdap vaccine in the case of routine vaccination (the Government covers the cost)?
	Yes	No	Unsure	No answer	P-value
Ob/Gyn	444 (92.1%)	32 (6.6%)	2 (0.4%)	4 (0.8%)	0.673
Pediatrics	428 (92.8%)	24 (5.2%)	3 (0.7%)	6 (1.3%)
Total	872 (92.5%)	56 (5.9%)	5 (0.5%)	10 (1.1%)

P-values were calculated by the proportion of questions answered “yes” in both departments.

Pregnant women who presented to the Obstetrics and Gynecology Department and participated in the study comprised the Ob/Gyn group, while mothers whose children presented to the Pediatric Department comprised the Pediatrics group.

Ob/Gyn; Obstetrics and Gynecology.

Table 2. Participant’s comments.

I would like more information, including about preservatives, additives, and any serious adverse events.

I will have the maternal vaccine once it is approved, included in the NIP, and has been to shown to have no adverse events.

I want to have the maternal vaccine if it has no side effects, like the HPV vaccine.

I will have the maternal vaccine, although the possibility of side effects is concerning.

I will have the maternal vaccine if it is proved to be safe.

I will not have the vaccine unless I have had known pertussis contacts.

I have not decided yet because it is too expensive.

I will have the vaccine, but I want the vaccine fee to be reduced.

I have not had the vaccine because the incidence rate of pertussis is not known.

I have not had the vaccine because the incidence rate of neonatal pertussis and the risk for maternal health is not known. It can be prevented by not taking babies outside.