Willingness of parents to vaccinate their 6–60-month-old children with EV71 vaccines: a cross-sectional study in rural areas of northern Jiangsu Province

Figures & data

Table 1. Demographic characteristics of participants.

Parameter	N (%)
Parental sex
Male	356 (32.0)
Female	756 (68.0)
Mean parental age ± SD, years	30.87 ± 5.27
20–29	504 (45.3)
30–39	524 (47.1)
≥40	84 (7.6)
Education level
Primary school or lower	110 (9.9)
Junior/senior high school	851 (76.5)
University graduate or higher	151 (13.6)
Occupation
Farmer	273 (24.5)
Private employee	360 (32.4)
Civil servant	38 (3.4)
Freelancer	441 (39.7)
Mean monthly household income ± SD, RMB	6,603.53 ± 3,927.94
Missing date	5 (0.5)
Children’s sex
Male	586 (52.7)
Female	526 (47.3)
Mean age of children ± SD, months	31.42 ± 14.99
Number of brothers and sisters
0	487 (43.8)
≥1	625 (56.2)
Having child who suffered from HFMD
Yes	158 (14.2)
No	954 (85.8)
Missing date	4 (0.4)

SD, standard deviation; N (%), number (percentage) of participants in each category.

Table 2. Knowledge and attitude about HFMD or EV71 vaccines and associated with the willingness to vaccinate their children with HFMD vaccines.

Parameter	TotalN (%)	Willing to vaccinate with EV71 vaccinesn (%)	Unadjusted OR	95%CI for OR	P
County
Sheyang	360 (32.4)	287 (29.4)	1.00
Ganyu	358 (32.2)	324 (33.2)	0.41	0.27-0.64	0.0000
Xinyi	394 (35.4)	365 (37.4)	0.31	0.20-0.49	0.0000
Parental sex
Male	356 (32.0)	309 (31.7)	1.00
Female	756 (68.0)	667 (68.3)	0.88	0.60-1.28	0.4974
Parental age (years)
20-29	504 (45.3)	456 (46.7)	1.00
30-39	524 (47.1)	457 (46.8)	1.39	0.94-2.06	0.0982
≥40	84 (7.6)	63 (6.5)	3.17	1.78-5.64	0.0001
Education level
Primary school or lower	110 (9.9)	85 (8.7)	1.00
Junior / Senior high school	851 (76.5)	748 (76.6)	0.47	0.29-0.77	0.0020
University graduate or higher	151 (13.6)	143 (14.7)	0.19	0.08-0.44	0.0001
Occupation
Farmer	273 (24.5)	238 (24.4)	1.00
Private employee	360 (32.4)	307 (31.4)	1.17	0.74-1.86	0.4937
Civil servant	38 (3.4)	34 (3.5)	0.80	0.27-2.39	0.6896
Freelancer / Unemployed	441 (39.7)	397 (40.7)	0.75	0.47-1.21	0.2403
Monthly household income (RMB)
<4000	187 (16.8)	165 (16.9)	1.00
4000~7999	565 (50.8)	493 (50.5)	1.10	0.66-1.82	0.7258
≥8000	360 (32.4)	318 (32.6)	0.99	0.57-1.72	0.9730
Having family member who engaged in medicine
Yes	242 (21.8)	39 (4.0)	1.00
No	870 (78.2)	937 (96.0)	1.37	0.48-3.91	0.5517
Children’s sex
Male	586 (52.7)	511 (52.4)	1.00
Female	526 (47.3)	465 (47.6)	0.89	0.62-1.28	0.5416
Children’s age (months)
6~11	126 (11.3)	110 (11.3)	1.00
12~23	259 (23.3)	239 (24.5)	0.58	0.29-1.15	0.1190
24~35	299 (26.9)	253 (25.9)	1.25	0.68-2.30	0.4743
36~47	247 (22.2)	218 (22.3)	0.92	0.48-1.76	0.7883
48~60	181 (16.3)	156 (16.0)	1.10	0.56-2.16	0.7779
Attend kindergarten
Yes	308 (27.7)	270 (27.7)	1.00
No	804 (72.3)	706 (72.3)	0.99	0.66-1.47	0.9460
Number of brothers and sisters
0	487 (43.8)	428 (43.8)	1.00
≥1	625 (56.2)	548 (56.2)	1.02	0.71-1.46	0.9175
Having child who suffered from HFMD
Yes	158 (14.2)	137 (14.0)	1.00
No	954 (85.8)	839 (86.0)	0.89	0.54-1.47	0.6605
Mean knowledge of HFMD ± SD, scores	3.4 ± 1.7	3.5 ± 1.7	0.80	0.72-0.89	0.0000
Mean knowledge of EV71 vaccines ± SD, scores	0.8 ± 1.2	0.9 ± 1.2	0.78	0.66-0.93	0.0059
Consider children are not susceptible to HFMD
Yes	242 (21.8)	199 (20.4)	1.00
No	870 (78.2)	777 (79.6)	0.55	0.37-0.82	0.0033
Consider HFMD is not serious
Yes	311 (28.0)	244 (25.0)	1.00
No	801 (72.0)	732 (75.0)	0.34	0.24-0.50	0.0000
Consider EV71 vaccines is expensive
Yes	858 (77.2)	751 (76.9)	1.00
No	254 (22.8)	225 (23.1)	0.91	0.59-1.40	0.6527

n (%), number (percentage) of participants who were willing to vaccinate their children in each category; unadjusted OR, unadjusted odds ratio; 95% CI, 95% confidence interval.

Table 3. Final model of factors associated with the parental willingness to vaccinate their children.

Parameter	P	Adjusted OR	95% CI for OR
County (Sheyang)
Ganyu	0.0033	0.50	0.31–0.79
Xinyi	0.0000	0.33	0.20–0.53
Parental age (20–29) (years)
30–39	0.2933	1.25	0.83–1.88
≥40	0.0194	2.12	1.13–3.97
Education level (primary school or lower)
Junior/senior high school	0.0965	0.64	0.37–1.08
University graduate or higher	0.0030	0.26	0.11–0.64
Good knowledge of EV71 vaccines	0.0279	0.81	0.67–0.98
Consider children are not susceptible to
HFMD (yes)
No	0.0218	0.61	0.40–0.93
Consider HFMD is not serious (yes)
No	0.0000	0.43	0.29–0.63