Incidence of varicella and herpes zoster after inclusion of varicella vaccine in national immunization schedule in Turkey: time trend study

Figures & data

Table 1. Incidence of varicella with respect to age stratas and years

YEAR	No of total patient population	No. of children age ≤ 5 years admitted	No. (%) children diagnosis with varicella age ≤ 5 years	Incidence of varicella per 100000 children age ≤ 5 years	No. of children age 6–17 years admitted	No. (%) children diagnosis with varicella age 6–17 years	Incidence of varicella per 100000 children age 6–17 years	No. of patient age > 17 years admitted	No. (%) patient diagnosis with varicella age > 17 years	Incidence of varicella per 100000 patient age > 17 years
2011	91965	10323	30	290	5038	43	853	76604	4	52
2012	110205	11844	43	363	5646	41	726	92715	8	8
2013	112785	14489	52	358	6897	67	971	91403	21	22
2014	118248	15491	30	193	8906	35	392	93851	5	5
2015	122183	15613	28	179	8205	48	585	98365	13	13
2016	128305	16122	21	130	9571	52	543	102612	7	6
2017	136317	17906	12	67	10479	36	343	107932	15	13
2018	132831	18140	4	22	11558	25	216	103133	9	8
2019	138254	16029	4	24	15280	26	170	106975	5	4

Table 2. Varicella vaccine immunization status of study population with respect to age stratas

Year	Children age ≤ 5 years	Children age 6–17 years	Patient age ≥ 18 years
2011	None	None	None
2012	None	None	None
2013*	Yes for children age ≤ 12 months	None	None
2014	Yes for children age ≤ 24 months	None	None
2015	Yes for children age ≤ 36 months	None	None
2016	Yes for children age ≤ 48 months	None	None
2017	Yes for children age ≤ 60 months	None	None
2018	All	Yes for children age ≤ 12 months	None
2019	All	Yes for children age ≤ 24 months	None

*Varicella vaccination introduced Turkish national immunization program in year 2013. World Health Organization (WHO) reported a national coverage for the Varicella vaccine 97% in 2013, 96% in 2014, 97% in 2015, 98% in 2016, 96% in 2017 and in 2018.

Figure 1. The incidences of varicella with respect to age stratas (year) by calendar year 2011–2019

Table 3. Incidence of Herpes Zoster with respect to age stratas and years

YEAR	No. of children age ≤ 5 years admitted	No. (%) children diagnosis with zoster age ≤ 5 years	Incidence of zoster per 100000 children age ≤ 5 years	No. of children age 6–17 years admitted	No. (%) children diagnosis with zoster age 6–17 years	Incidence of zoster per 100000 children age 6–17 years	No. of patient age > 17 years admitted	No. (%) patient diagnosis with zoster age > 17 years	Incidence of zoster per 100000 patient age > 17 years
2011	10323	1	9	5038	1	19	76604	140	182
2012	11844	4	33	5646	8	141	92715	184	198
2013	14489	0	0	6897	4	57	91403	186	203
2014	15491	1	6	8906	3	33	93851	184	196
2015	15613	0	0	8205	3	36	98365	223	226
2016	16122	3	18	9571	4	41	102612	235	229
2017	17906	3	16	10479	3	28	107932	244	226
2018	18140	5	27	11558	5	43	103133	249	241
2019	16029	6	37	15280	9	58	106975	305	285

Figure 2. The incidences of Herpes Zoster with respect to age stratas by calendar year 2011–2019

Table 4. Incidences of Herpes Zoster with respect to adulthood age stratas by calendar year

YEAR	No. of patients age 18–44 years admitted	No. (%) patients diagnosis with zoster age 18–44 years	Incidence of zoster per 100000 patients age 18–44 years	No. of patients age 45–64 years admitted	No. (%) patients diagnosis with zoster age 45–64 years	Incidence of zoster per 100000 patients age 45–64 years	No. of patient age > 65 years admitted	No. (%) patient diagnosis with zoster age ≥ 65 years	Incidence of zoster per 100000 patient age ≥ 65 years
2011	39756	83	208	24758	35	141	12090	22	181
2012	52849	119	225	26922	41	152	12944	22	169
2013	62403	120	192	15757	52	330	13243	16	120
2014	51795	118	227	28921	40	138	13135	28	213
2015	54544	128	234	30233	62	205	13588	33	242
2016	61785	151	244	26393	60	227	14434	28	193
2017	64431	149	231	28340	57	201	15161	38	250
2018	63361	158	249	23720	62	261	16052	32	199
2019	62012	188	303	28281	89	314	16682	34	203