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Human Vaccines & Immunotherapeutics Volume 17, 2021 - Issue 8
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Research Paper

Acute disseminated encephalomyelitis and routine childhood vaccinations – a self-controlled case series

T. J. Martina Department of Paediatrics, Monash University, Clayton, Australia;b Surveillance of Adverse Events Following Vaccination In the Community (SAEFVIC), Murdoch Children’s Research Institute (MCRI), Parkville, Australia;c Department of General Medicine, Royal Children’s Hospital (RCH), Parkville, Australia;d Department of Paediatrics, Monash Health, Clayton, AustraliaCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0001-8955-9190View further author information
ORCID Icon,
M. Faheya Department of Paediatrics, Monash University, Clayton, Australia;d Department of Paediatrics, Monash Health, Clayton, AustraliaORCID Iconhttps://orcid.org/0000-0003-0811-4785View further author information
ORCID Icon,
M. Eastonb Surveillance of Adverse Events Following Vaccination In the Community (SAEFVIC), Murdoch Children’s Research Institute (MCRI), Parkville, AustraliaORCID Iconhttps://orcid.org/0000-0003-0299-0573View further author information
ORCID Icon,
H. J. Clothierb Surveillance of Adverse Events Following Vaccination In the Community (SAEFVIC), Murdoch Children’s Research Institute (MCRI), Parkville, Australia;e School of Population & Global Health, University of Melbourne, Parkville, AustraliaORCID Iconhttps://orcid.org/0000-0001-7594-0361View further author information
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R. Samuela Department of Paediatrics, Monash University, Clayton, AustraliaView further author information
,
N. W. Crawfordb Surveillance of Adverse Events Following Vaccination In the Community (SAEFVIC), Murdoch Children’s Research Institute (MCRI), Parkville, Australia;c Department of General Medicine, Royal Children’s Hospital (RCH), Parkville, Australia;f Department of Paediatrics, The University of Melbourne, Parkville, AustraliaView further author information
&
J. P. Butterya Department of Paediatrics, Monash University, Clayton, Australia;b Surveillance of Adverse Events Following Vaccination In the Community (SAEFVIC), Murdoch Children’s Research Institute (MCRI), Parkville, Australia;c Department of General Medicine, Royal Children’s Hospital (RCH), Parkville, Australia;d Department of Paediatrics, Monash Health, Clayton, Australia;f Department of Paediatrics, The University of Melbourne, Parkville, AustraliaORCID Iconhttps://orcid.org/0000-0001-9905-2035View further author information
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Pages 2578-2585 | Received 02 Aug 2020, Accepted 04 Mar 2021, Published online: 09 Apr 2021

Figures & data

Table 1. Victorian immunization schedule for children up to 7 years of age at January 2015

Figure 1. Participant flowchart

Figure 1. Participant flowchart

Figure 2. ADEM cases, by month of symptom onset

Figure 2. ADEM cases, by month of symptom onset

Figure 3. Distribution of vaccinations per pathogen as recorded in ACIR

Figure 3. Distribution of vaccinations per pathogen as recorded in ACIR

Table 2. Relative incidences from the SCCS analyses

Table 3. Case details for vaccine proximate cases

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