Adoptive tumor infiltrating lymphocytes cell therapy for cervical cancer

Figures & data

Table 1. Clinical trials studying TIL therapy in cervical cancers.

No.	NCT Number	Title	Phases	Enrollment	Combined treatment	Status
1	NCT03108495	Study of LN-145, Autologous Tumor Infiltrating Lymphocytes in the Treatment of Patients With Cervical Carcinoma	Phase 2	138	pembrolizumab	Recruiting
2	NCT01585428	Immunotherapy Using Tumor Infiltrating Lymphocytes for Patients With Metastatic Human Papillomavirus-Associated Cancers	Phase 2	29	-	Completed
3	NCT04443296	Study of Tumor Infiltrating Lymphocytes Following CCRT in the Treatment of Patients With Cervical Carcinoma	Phase 1	10	CCRT	Active, not recruiting
4	NCT04674488	TILs for Treatment of Metastatic or Recurrent Cervical Cancer	Phase 1	15	-	Recruiting
5	NCT05107739	A Study of DeTIL-0255 in Adults With Advanced Malignancies	Phase 1		-	Recruiting

Figure 1. Versatility of TIL subclones.

Figure 2. Schematic illustration of anticancer response mediated by T cells in vivo.

Figure 3. Future immunotherapy pattern of adoptive cell therapy based on TIL culture which involves in diverse methods.