COVID-19 vaccine acceptance rate and its predictors in Ethiopia: A systematic review and meta-analysis

Figures & data

Figure 1. Flow diagram of articles selection and screening.

Table 1. Characteristics of studies included in this systematic review and meta-analysis.

Author/year of publication	Study area	Region	Study design	Study populations	Sample size	Proportion	Quality
Aemro A et al/2021^Citation22	Referral hospitals	Amhara	Cross-sectional	Health workers	440	54.1	Low risk
Mose A/2021^Citation29	Guragie hospitals	SNNPRS	cross-sectional	Lactating mothers	630	61	Low risk
Berihun G et al/2021^Citation26	South Wollo CSP	Amhara	cross-sectional	Patients	416	59.4	Low risk
Guangul BA et al/2021^Citation27	Health institutions	Online survey	Cross-sectional	Health workers	668	72.2	Low risk
Handebo S et al/2021^Citation28	High school	Amhara	Cross-sectional	High school teachers	323	54.8	Low risk
Angelo AT et al/2021^Citation23	Mizan Tepi University	SNNPRS	Cross-sectional	Health workers	405	48.4	Low risk
Abebe H et al/2021^Citation16	Guragie hospitals	SNNPRS	Cross-sectional	Adults	492	62.6	Low risk
Hailemariam S et al/2021^Citation13	Health institutions	SNNPRS	Cross-sectional	Pregnant mothers	423	31.3	Low risk
Taye BT et al/2021^Citation32	Debre Birhan university	Amhara	Cross-sectional	Students	423	69.3	Low risk
Belsti Y et al/2021^Citation24	Online survey	Online survey	Cross-sectional	Adults	1184	31.9	Low risk
Bereda G/2021^Citation25	Oromia zones	Oromia	Cross-sectional	Health workers	422	42.2	Low risk
Alle F/2021^Citation18	Debretabor hospital	Amhara	Cross-sectional	Health workers	327	42.3	Low risk
Zewude B et al/2021^Citation31	Wolayita Sodo	SNNPRS	Cross-sectional	Adults	319	46.1	Low risk
Shitu K et al/2021^Citation30	Gondar city	Amhara	Cross-sectional	School teachers	301	40.8	Low risk

Figure 2. Funnel plot of COVID-19 vaccine acceptance with 95% CI.

Figure 3. Forest plot of proportion of COVID-19 vaccine acceptance with 95% CI.

Figure 4. Forest plot of sub-group analysis of proportion by region.

Figure 5. Forest plot of sub-group analysis of proportion by study participants.

Figure 6. Forest plot of odds ratio of predictors of COVID-19 vaccine acceptance.

Aemro A, Amare NS, Shetie B, Chekol B, Wassie M. Determinants of COVID-19 vaccine hesitancy among health care workers in Amhara region referral hospitals, Northwest Ethiopia: a cross-sectional study. Epidemiol Infect. 2021;149. doi:10.1017/S0950268821002259.

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Mose A. Willingness to receive COVID-19 vaccine and its determinant factors among lactating mothers in Ethiopia: a cross-sectional study. Infect Drug Resist. 2021;14:4249. doi:10.2147/IDR.S336486.

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Berihun G, Walle Z, Berhanu L, Teshome D. Acceptance of COVID-19 vaccine and determinant factors among patients with chronic disease visiting Dessie comprehensive specialized hospital, Northeastern Ethiopia. Patient Prefer Adherence. 2021;15:1795. doi:10.2147/PPA.S324564.

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Guangul BA, Georgescu G, Osman M, Reece R, Derso Z, Bahiru A, Azeze ZB. Healthcare workers attitude towards SARS-COVID-2 vaccine, Ethiopia. Glob J Infect Dis Clin Res. 2021;7(1):043–8.

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Handebo S, Wolde M, Shitu K, Kassie A, Wang Z. Determinant of intention to receive COVID-19 vaccine among school teachers in Gondar City, Northwest Ethiopia. PloS One. 2021;16(6):e0253499. doi:10.1371/journal.pone.0253499.

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Angelo AT, Alemayehu DS, Dachew AM, Villar LM. Health care workers intention to accept COVID-19 vaccine and associated factors in southwestern Ethiopia, 2021. PloS One. 2021;16(9):e0257109. doi:10.1371/journal.pone.0257109.

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Abebe H, Shitu S, Mose A. Understanding of COVID-19 vaccine knowledge, attitude, acceptance, and determinates of COVID-19 vaccine acceptance among adult population in Ethiopia. Infect Drug Resist. 2021;14:2015. doi:10.2147/IDR.S312116.

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Hailemariam S, Mekonnen B, Shifera N, Endalkachew B, Asnake M, Assefa A, Qanche Q. Predictors of pregnant women’s intention to vaccinate against coronavirus disease 2019: a facility-based cross-sectional study in southwest Ethiopia. Sage Open Med. 2021;9:20503121211038454. doi:10.1177/20503121211038454.

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Taye BT, Amogne FK, Demisse TL, Zerihun MS, Kitaw TM, Tiguh AE, Mihret MS, Kebede AA. Coronavirus disease 2019 vaccine acceptance and perceived barriers among university students in northeast Ethiopia: a cross-sectional study. Clin Epidemiology Glob Health. 2021;12:100848. doi:10.1016/j.cegh.2021.100848.

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Belsti Y, Gela YY, Akalu Y, Dagnew B, Getnet M, Seid MA, Diress M, Yeshaw Y, Fekadu SA. Willingness of Ethiopian population to receive COVID-19 vaccine. J Multidiscip Healthc. 2021;14:1233. doi:10.2147/JMDH.S312637.

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Bereda G. Enthusiasm to acceptance of SARS_COV_2 vaccine among health care workers in Oromia Regional State, Ethiopia. An Online Based Cross-Sectional Study, 2021. 2021.

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Fentie Alle KEO Y. Attitude and associated factors of COVID-19 vaccine acceptance among health professionals in Debre Tabor Comprehensive Specialized Hospital, North Central Ethiopia; 2021: crosssectional study. Indian Virological Society. 2021;32(2):272-278. doi:10.1007/s13337-021-00708-0.

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Zewude B, Habtegiorgis T. Willingness to take COVID-19 vaccine among people most at risk of exposure in Southern Ethiopia. Pragmat Obs Res. 2021;12:37. doi:10.2147/POR.S313991.

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Shitu K, Wolde M, Handebo S, Kassie A. Acceptance and willingness to pay for COVID-19 vaccine among school teachers in Gondar City, Northwest Ethiopia. Trop Med Health. 2021;49(1):1–12. doi:10.1186/s41182-020-00291-y.

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Data availability statement

All data generated or analyzed during study are included in this systematic review and meta-analysis.