Anti-NMDAR Encephalitis

ABSTRACT

Anti-N-methyl-D-aspartate receptor encephalitis is a newly described disease process. Patients are generally young females who present with psychiatric symptoms and progress to have seizures, abnormal movements, and autonomic instability. Diagnosis is made based on serum and cerebrospinal fluid results. However, a characteristic EEG pattern described as extreme delta brush has been associated with this disorder, making it especially relevant to neurodiagnostic technologists in practice today. Our case presentations follow two patients through the course of their illness and recovery.

KEY WORDS:

• Anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis
• extreme delta brush
• psychiatric symptoms
• seizures
• teratoma