Figures & data
Table 1. Particle size, zeta potential, and entrapment efficiency(EE) of the prepared liposomes
Figure 1. TEM images of plain liposomes (a), 5-FU loaded liposomes (b) 5-FUC loaded liposomes (c). (Bar = 200 nm)
Figure 2. Release profiles of 5-FU and 5-FUC from liposomes. Data were expressed as mean ± SD, n = 3 in each group
Figure 3. SDS polyacrylamide gel electrophoresis of the LDL. Lane M, show band corresponding to standard proteins with varying molecular weights (Da). Lane 6 and 7 were samples from separated LDL
Table 2. Particle size, zeta potential, and entrapment efficiency(EE) of plain LDL as well as drugs loaded LDL
Figure 4. TEM images of plain LDL (a), 5-FU loaded LDL (b) 5-FUC loaded LDL (c). (Bar = 50 nm)
Figure 5. Transfer percentage of 5-FU and 5- FUC into LDL using the liposome loading method. (a) after 2 h incubation time, (b) after 4 h incubation time
Figure 6. Effect of the 5-FUC solution, 5-FUC loaded liposomes, and 5-FUC loaded LDL on HepG2 line cell viability after, 24 h (a), 48 (b) 72 h (c) incubation time
Table 3. Deposition of drugs from 5-FU and 5-FUC liposomes into LDL, and liver tissues after 2 h and 4 h of drug intraperitoneal injection