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Research Paper

Effect of sodium butyrate regulating IRAK1 (interleukin-1 receptor-associated kinase 1) on visceral hypersensitivity in irritable bowel syndrome and its mechanism

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Pages 1436-1444 | Received 19 Jan 2021, Accepted 17 Apr 2021, Published online: 27 Apr 2021

Figures & data

Figure 1. Visceral sensitivity of three groups of mice

Figure 1. Visceral sensitivity of three groups of mice

Figure 2. Staining results of colon transverse section of three groups of mice (a): IBS model group; (b): sodium butyrate group; (c): blank control group)

Figure 2. Staining results of colon transverse section of three groups of mice (a): IBS model group; (b): sodium butyrate group; (c): blank control group)

Figure 3. Expression of IRAK1 protein in colon epithelial cells of mice ((a): comparison of sample number, positive and negative number of mice in three groups; (b): comparison of mean value of three groups of mice)

Figure 3. Expression of IRAK1 protein in colon epithelial cells of mice ((a): comparison of sample number, positive and negative number of mice in three groups; (b): comparison of mean value of three groups of mice)

Figure 4. Relationship between IRAK1 content in colon tissue and visceral pain threshold in mice

Figure 4. Relationship between IRAK1 content in colon tissue and visceral pain threshold in mice

Figure 5. IRAK1 protein expression in HT-29 cells of different groups

Figure 5. IRAK1 protein expression in HT-29 cells of different groups
Supplemental material

Supplemental Material

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Data availability statement

Some or all data, models, or code generated or used during the study are available from the corresponding author by request.