Self-assembled chitosan nanoparticles for intranasal delivery of recombinant protein interleukin-17 receptor C (IL-17RC): preparation and evaluation in asthma mice

Figures & data

Figure 1. Expression and identification of rIL-17RC protein

Figure 2. Characteristics of nanoparticles

Table 1. Expression of ALT, AST, and BUN

Groups	ALT (U/L)	AST (U/L)	BUN (mmol/L)
PBS	5.12 ± 0.87	18.12 ± 1.12	6.01 ± 0.77
rIL-17RC	5.20 ± 0.34	20.45 ± 2.48	6.30 ± 0.30
CS	5.66 ± 1.40	20.66 ± 2.15	5.88 ± 0.53
CS-RC	5.86 ± 0.56	21.54 ± 0.72	6.32 ± 0.48

Note: ALT (0–72.3 U/L), AST (0–72.3 U/L), BUN (0.5–35 U/L)

Figure 3. Effect of CS-RC nanoparticles on cytokine and chemokine expression in BALF

Figure 4. Histopathological analysis of the lung tissues