Analysis of role of rat cerebral pericytes in cerebral vasospasm after subarachnoid hemorrhage and molecular mechanism of neurovascular injury

Figures & data

Table 1. Zeal-Longa five-point scale scoring method

Score	Evaluation standard
0	The limbs are bilaterally symmetrical and behave normally, and respond quickly when touching the body without obvious neurological deficits.
1	Relatively little activity, the limb activity shows a slight bilateral asymmetry, the response is not rapid when touching the body, and the neurological deficit is not obvious.
2	Less activity, limb activity shows bilateral asymmetry, the reaction is slow when touching the body, and the neurological deficit is more obvious.
3	Very little activity, limb activity shows obvious bilateral asymmetry, unresponsiveness when touching the body, and obvious neurological deficits.
4	Almost no activity, almost no response to touch, neurological deficit.

Figure 1. Results of evaluation of neurologic impairment

(Note: *represented a significant difference from group A (control group), P < 0.05; # represented a significant difference from group A and group C at the same time, P < 0.05.)

Figure 2. Comparison of number of micro-vasoconstrictions after operation

(* meant that there was statistically considerable difference, P < 0.05.)

Figure 3. Comparison of the degree of micro-vasoconstriction after operation

(* meant that there was statistically considerable difference, P < 0.05.)

Figure 4. Fluorescence imaging in vivo

(Note: the yellow circle in the figure indicated the artery lumen.)

Figure 5. BBB permeability test results

(* meant that there was statistically considerable difference, P < 0.05.)

Figure 6. Comparison of brain slices

(Note: * in the figure represented the arterial lumen; the triangles represented blood clots in the subarachnoid space; the middle column was the general image, and the last column was the partial enlarged image.)

Figure 7. Comparison of the expression results of α-SMA in pericytes of each group

Figure 8. Nitric oxide content in blood of rats after SAH operation