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Research Paper

Estimation of polymorphisms in the drug-metabolizing enzyme, cytochrome P450 2C19 gene in six major ethnicities of Pakistan

ORCID Icon, , ORCID Icon, , , , , & show all
Pages 4442-4451 | Received 13 Apr 2021, Accepted 17 Jun 2021, Published online: 24 Jul 2021

Figures & data

Figure 1. Ribbon struture of CYP2C19 enzyme

Figure 1. Ribbon struture of CYP2C19 enzyme

Table 1. Allelic frequencies of CYP2C19*2 allele along with confidence intervals (CI) in various ethnic groups in the Pakistani population

Figure 2. Geographical representation of the ethnicities investigated in the study and their respective CYP2C19*2, and *3 allelic frequencies. The figure was created using CorelDRAW Graphic Suite 2020 (https://www.coreldraw.com/en/)

Figure 2. Geographical representation of the ethnicities investigated in the study and their respective CYP2C19*2, and *3 allelic frequencies. The figure was created using CorelDRAW Graphic Suite 2020 (https://www.coreldraw.com/en/)

Figure 3. CYP2C19*2 genotype frequencies in various ethnic groups of Pakistan

Figure 3. CYP2C19*2 genotype frequencies in various ethnic groups of Pakistan

Table 2. Allelic frequencies of CYP2C19*3 allele along with confidence intervals (CI) in various ethnic groups in the Pakistani population

Figure 4. CYP2C19*3 genotype frequencies in various ethnic groups of Pakistan

Figure 4. CYP2C19*3 genotype frequencies in various ethnic groups of Pakistan

Table 3. Comparison of CYP2C19*2 allelic frequencies observed in Pakistan with other populations

Table 4. Comparison of CYP2C19*3 allelic frequencies observed in Pakistan with other populations

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