Figures & data
Figure 1. The workflow of the study
Figure 2. A cluster heat map of each protein identified by two repeated tandem mass tag labeling
Figure 3. Upregulation (red) and downregulation (blue) of protein expression in the circle heat map of 89 DEPs
Figure 4. The 23 biological processes, 12 cell components, and three molecular functions. The size of the dot represents the number of genes contained in the GO function; the color represents the P value. The redder the color, the smaller the P value, and the greener the color, the larger the P value
Figure 5. Topological screening for the PPI network
Figure 6. Lung tissues subjected to HE staining and observed under a light microscope at 200× and 400× magnifications. Representative images of each group are shown at scale bars of 100 μm and 50 μm. Sham indicates the sham group, model as the ARDS rat model control, and special electromagnetic field-treated water (SEW) and far-infrared radiation (FIR) as the SEW and FIR group
Figure 7. (a) The result of PRM verification. Compared with the model group, the expression of Hp was restored after treatment with SEW and FIR, n = 6. (B, C, and D) The result of ELISA. Compared with the sham group, the expression level of Hp, IL-6, and IL-1β in BALF in the model group was significantly increased (P < 0.01). Compared with the model group, the expression level of Hp, IL-6, and IL-1β in the SEW and FIR group was significantly decreased
Figure 8. Possible regulatory mechanisms of SEW and FIR to alleviate ARDS
Supplemental Material
Download ()Availability of data and material
Publicly available datasets were analyzed in this study. These data can be found in the repository iProX, with accession ID IPX0002375000 (http://www.iprox.org).
