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Bioengineered Volume 12, 2021 - Issue 1
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Research Paper

Transcription factor 3 (TCF3) combined with histone deacetylase 3 (HDAC3) down-regulates microRNA-101 to promote Burkitt lymphoma cell proliferation and inhibit apoptosis

Lihua DongDepartment of Hematology, Henan Institute of Hematology, the Affiliated Cancer Hospital of Zhengzhou University, Zhengzhou, Henan Province, ChinaCorrespondence[email protected]
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,
Jingjing HuangDepartment of Hematology, Henan Institute of Hematology, the Affiliated Cancer Hospital of Zhengzhou University, Zhengzhou, Henan Province, ChinaView further author information
,
Peng ZuDepartment of Hematology, Henan Institute of Hematology, the Affiliated Cancer Hospital of Zhengzhou University, Zhengzhou, Henan Province, ChinaView further author information
,
Jing LiuDepartment of Hematology, Henan Institute of Hematology, the Affiliated Cancer Hospital of Zhengzhou University, Zhengzhou, Henan Province, ChinaView further author information
,
Xue GaoDepartment of Hematology, Henan Institute of Hematology, the Affiliated Cancer Hospital of Zhengzhou University, Zhengzhou, Henan Province, ChinaView further author information
,
Jianwei DuDepartment of Hematology, Henan Institute of Hematology, the Affiliated Cancer Hospital of Zhengzhou University, Zhengzhou, Henan Province, ChinaView further author information
&
Yufu LiDepartment of Hematology, Henan Institute of Hematology, the Affiliated Cancer Hospital of Zhengzhou University, Zhengzhou, Henan Province, ChinaView further author information
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Pages 7995-8005 | Received 29 Jul 2021, Accepted 03 Sep 2021, Published online: 17 Oct 2021

Figures & data

Table 1. Primer sequence

Figure 1. The expression of TCF3 and miR-101 in Burkitt lymphoma tissues and lymphoma cells

Figure 1. The expression of TCF3 and miR-101 in Burkitt lymphoma tissues and lymphoma cells

Figure 2. Influence of BL cell proliferation, apoptosis, cell cycle and Akt/mTOR pathway by knocking down TCF3

Figure 2. Influence of BL cell proliferation, apoptosis, cell cycle and Akt/mTOR pathway by knocking down TCF3

Figure 3. The effect of miR-101 on lymphoma cell proliferation, apoptosis, cell cycle and Akt/mTOR pathway

Figure 3. The effect of miR-101 on lymphoma cell proliferation, apoptosis, cell cycle and Akt/mTOR pathway

Figure 4. The expression level of miR-101 after knocking down HDAC3 and TCF3

Figure 4. The expression level of miR-101 after knocking down HDAC3 and TCF3

Figure 5. The relationship between TCF3, HDAC3 and miR-101

Figure 5. The relationship between TCF3, HDAC3 and miR-101

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