Figures & data
Figure 1. Effects of soy isoflavones on body weight and ovarian weight of PCOS rats. A, Changes of body weight of rats in each group; B-C, Changes of ovarian weight and volume of rats in each group after 4 weeks of soy isoflavones treatment in PCOS rats. * P < 0.05 and ** P < 0.01 vs. Control group; # P < 0.05 and ## P < 0.01 vs. PCOS group. PCOS, Polycystic ovary syndrome; MET, Metformin; SI, soy isoflavones
Figure 2. Effect of soy isoflavones on estrus cycle of PCOS rats PCOS, polycystic ovary syndrome; MET, Metformin; SI, soy isoflavones
Figure 3. Effect of soy isoflavones on ovarian histological morphology of PCOS rats Magnification, 100 × . PCOS, Polycystic ovary syndrome; MET, Metformin; SI, soy isoflavones
Figure 4. Effects of soy isoflavones on serum hormone levels of PCOS rats. A, Biochemical test of serum testosterone (T) levels of rats; B, Biochemical test of serum estradiol hormone (E2) levels of rats; C, Biochemical test of serum luteinizing hormone (LH) levels of rats; D, Biochemical test of the levels of follicle-stimulating hormone (FSH) in serum of rats; E, LH/FSH ratio.* P < 0.05 and ** P < 0.01 vs. Control group; # P < 0.05 vs. PCOS group. PCOS, Polycystic ovary syndrome; MET, Metformin; SI, soy isoflavones
Figure 5. Effects of soy isoflavones on oxidative stress and inflammatory cytokines in ovarian tissues of PCOS rats. A-C, Biochemical detection of MDA, SOD and GPX levels in rat ovarian tissue; D-F, ELISA determination of the levels of TNF-α, IL-1β and IL-6 in ovarian tissue of rats. *P < 0.05 the and * * P < 0.01 vs Control group; #P < 0.05 vs. PCOS group. PCOS, Polycystic ovary syndrome; MET, Metformin; SI, soy isoflavones
Figure 6. Effect of soy isoflavones on NF-κB signaling pathway in ovarian tissue of PCOS rats
