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Bioengineered Volume 13, 2022 - Issue 4
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Research Paper

Matrine impedes colorectal cancer proliferation and migration by downregulating endoplasmic reticulum lipid raft associated protein 1 expression

Hongtao Rena Department of Radiotherapy, Second Affiliated Hospital of Xi’an Jiaotong University, Xi’an, ChinaView further author information
,
Yali Wanga Department of Radiotherapy, Second Affiliated Hospital of Xi’an Jiaotong University, Xi’an, ChinaView further author information
,
Ya Guoa Department of Radiotherapy, Second Affiliated Hospital of Xi’an Jiaotong University, Xi’an, ChinaView further author information
,
Mincong Wanga Department of Radiotherapy, Second Affiliated Hospital of Xi’an Jiaotong University, Xi’an, ChinaView further author information
,
Xiulong Maa Department of Radiotherapy, Second Affiliated Hospital of Xi’an Jiaotong University, Xi’an, ChinaView further author information
,
Wen Lia Department of Radiotherapy, Second Affiliated Hospital of Xi’an Jiaotong University, Xi’an, ChinaView further author information
,
Yuyan Guoa Department of Radiotherapy, Second Affiliated Hospital of Xi’an Jiaotong University, Xi’an, ChinaView further author information
&
Yiming Lib Department of General Surgery, Second Affiliated Hospital of Xi’an Jiaotong University, Xi’an, ChinaCorrespondence[email protected]
View further author information
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Pages 9780-9791 | Received 24 Nov 2021, Accepted 25 Mar 2022, Published online: 12 Apr 2022

Figures & data

Figure 1. Martine downregulated Erlin1 in CRC cells.

Figure 1. Martine downregulated Erlin1 in CRC cells.

Figure 2. Erlin1 was strongly upregulated in CRC tissues.

Figure 2. Erlin1 was strongly upregulated in CRC tissues.

Figure 3. Erlin1 knockdown suppressed CRC progression.

Figure 3. Erlin1 knockdown suppressed CRC progression.

Figure 4. Overexpression of Erlin1 promoted CRC proliferation and migration which can be reduced by matrine.

Figure 4. Overexpression of Erlin1 promoted CRC proliferation and migration which can be reduced by matrine.

Figure 5. Erlin1 knockdown enhanced anti-tumor effects of matrine in CRC cells.

Figure 5. Erlin1 knockdown enhanced anti-tumor effects of matrine in CRC cells.

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