Figures & data
Figure 1 Trial setup. Patient (left image) sitting in front of a computer screen, with a standard webcam (right image, 1) placed on top. Different tasks are presented on-screen using a moving dot as a visual stimulus (2). During the tasks, oculometric measures extraction and eye movement analysis are presented in the operator’s screen (Citation3).
![Figure 1 Trial setup. Patient (left image) sitting in front of a computer screen, with a standard webcam (right image, 1) placed on top. Different tasks are presented on-screen using a moving dot as a visual stimulus (2). During the tasks, oculometric measures extraction and eye movement analysis are presented in the operator’s screen (Citation3).](/cms/asset/5f211f85-f90c-42c5-9d7b-ecc2ec451377/iafd_a_2196315_f0001_c.jpg)
Figure 2 Correlation between ALSFRS-R scores and corrective saccadic latency (ms; R = 0.52, p = 0.002, y = 2.2x + 22.07). Each dot represents a single patient.
![Figure 2 Correlation between ALSFRS-R scores and corrective saccadic latency (ms; R = 0.52, p = 0.002, y = 2.2x + 22.07). Each dot represents a single patient.](/cms/asset/ec217642-8686-45d5-8aee-7776f4c3c8bd/iafd_a_2196315_f0002_b.jpg)
Figure 3 Fixation time (in ms) during smooth pursuit tasks of ALS patients (left) versus healthy subjects (right, p = 0.01).
![Figure 3 Fixation time (in ms) during smooth pursuit tasks of ALS patients (left) versus healthy subjects (right, p = 0.01).](/cms/asset/7beb38d2-54de-4619-8eb1-aad10129b399/iafd_a_2196315_f0003_b.jpg)
Figure 4 Peak velocity (degree/ms) in pro-saccade eye movement of ALS patients (left) versus healthy subjects (right, p = 0.04).
![Figure 4 Peak velocity (degree/ms) in pro-saccade eye movement of ALS patients (left) versus healthy subjects (right, p = 0.04).](/cms/asset/1326da7a-5c01-489d-9039-e5e8dcc3a20b/iafd_a_2196315_f0004_b.jpg)
Figure 5 Pro-saccade gain (%) of ALS patients with (left) versus without (middle, p = 0.01) bulbar symptoms and healthy subjects (right, p = 0.02).
![Figure 5 Pro-saccade gain (%) of ALS patients with (left) versus without (middle, p = 0.01) bulbar symptoms and healthy subjects (right, p = 0.02).](/cms/asset/f270c3ea-717f-4251-9ac0-6880f9111cb1/iafd_a_2196315_f0005_b.jpg)
Figure 6 Anti-saccade error rate (%) of ALS patients with (left) versus without bulbar symptoms (middle, p = 0.04) and versus healthy subjects (right, p = 0.01).
![Figure 6 Anti-saccade error rate (%) of ALS patients with (left) versus without bulbar symptoms (middle, p = 0.04) and versus healthy subjects (right, p = 0.01).](/cms/asset/ef5cd469-5c28-4ebb-9472-d375536c8465/iafd_a_2196315_f0006_b.jpg)