Green and rapid synthesis of silver nanoparticles using Borago officinalis leaf extract: anticancer and antibacterial activities

Figures & data

Figure 1. Graph illustrates the overview of biosynthesis of stable AgNPs from Borago officinalis leaf extract and their potential applications.

Figure 2. UV–Vis spectra of reaction mixture.

Figure 3. (A and B) FE-TEM images of AgNPs, (B and C) elemental mapping results indicate distribution of elements silver.

Figure 4. (A) EDX spectrum, (B) XRD spectrum of AgNPs, inset shows SAED pattern, respectively.

Figure 5. Representative FTIR spectra of plant extract and AgNPs.

Figure 6. (A) DLS result, (B) Zeta potential result of AgNPs.

Figure 7. Effect of different concentration of AgNPs on cell viability of RAW 264.7 macrophages cell line, A549 lung cancer cell line and HeLa cervical cancer cell line, respectively.

Figure 8. (A) Zones of inhibition against Pseudomonas aeruginosa [KACC 14021], Escherichia coli [CCARM 0237], Vibrio parahaemolyticus [KACC 15069] and Staphylococcus aureus [KCTC 3881], respectively. (B) Biofilm inhibition by AgNPs against S. aureus [KCTC 3881] and P. aeruginosa [KACC 14021].

Table 1. Antimicrobial activity of the silver nanoparticles synthesized from Borago officinalis leaf extract.

Pathogenic bacteria	Zone of inhibition (mm)
Pseudomonas aeruginosa	13.7 ± 0.5
Escherichia coli	11.0 ± 0.8
Vibrio parahaemolyticus	12.7 ± 0.5
Staphylococcus aureus	12.7 ± 0.5