Aluminum hydroxide nanoparticles show strong activity to stimulate Th-1 immune response against tuberculosis

Figures & data

Figure 1. Scanning electron microscope of Esx-V adsorbed of aluminum hydroxide nanoparticles.

Figure 2. Protein adsorption to nanoparticles was measured by SDS-PAGE. Lane 1, 2, and 3: EsxV to nanoparticles ratio was 1:1 and measured after 10, 30 minutes, and overnight. Lane 5, 6, and 7: amount of nanoparticles increased to 3-fold. The lane 4 was unbound protein.

Figure 3. IFN-γ release from splenic lymphocytes of immunized mice.

Figure 4. IL-4 release from splenic lymphocytes of immunized mice.

Figure 5. TGF-beta release from splenic lymphocytes of immunized mice.