Figures & data
![](/cms/asset/b19f9974-cecd-40e2-8f81-424ed3314c82/ianb_a_1241794_uf0001_c.gif)
Figure 1. Particle size distribution (a), zeta potential value (b), and scanning electron microscopy image of optimized formulation (c).
![Figure 1. Particle size distribution (a), zeta potential value (b), and scanning electron microscopy image of optimized formulation (c).](/cms/asset/17a17808-9a8f-4440-b937-a445b0b63953/ianb_a_1241794_f0001_b.jpg)
Figure 2. The X-ray diffractions pattern of precirol (a), Poloxamer® (b), arginine (c), and nanostructured lipid carrier formulation (d).
![Figure 2. The X-ray diffractions pattern of precirol (a), Poloxamer® (b), arginine (c), and nanostructured lipid carrier formulation (d).](/cms/asset/a02ed60f-8c0a-4f15-9f3f-e354b09822f4/ianb_a_1241794_f0002_b.jpg)
Figure 3. The Fourier transform infrared spectroscopy pattern of arginine (a), oleic acid (b), and the mixture of arginine-oleic acid (c).
![Figure 3. The Fourier transform infrared spectroscopy pattern of arginine (a), oleic acid (b), and the mixture of arginine-oleic acid (c).](/cms/asset/e4db40c2-aae3-4e03-89e3-df5d20e8ac39/ianb_a_1241794_f0003_b.jpg)
Figure 4. In vitro drug release profile of arginine-loaded nanostructured lipid carrier formulation (Data are presented as mean ± SD).
![Figure 4. In vitro drug release profile of arginine-loaded nanostructured lipid carrier formulation (Data are presented as mean ± SD).](/cms/asset/00c01a31-4035-4cea-a10f-04cbaa614e33/ianb_a_1241794_f0004_b.jpg)
Figure 5. Rhodamine B penetration into hamster skin: staining of hamster skin following the application of 0.001% Rhodamine B solution (a: light microscopic image, b: fluorescent microscopic image) and 0.001% Rhodamine B-loaded nanostructured lipid carrier (c: light microscopic image, d: fluorescent microscopic image).
![Figure 5. Rhodamine B penetration into hamster skin: staining of hamster skin following the application of 0.001% Rhodamine B solution (a: light microscopic image, b: fluorescent microscopic image) and 0.001% Rhodamine B-loaded nanostructured lipid carrier (c: light microscopic image, d: fluorescent microscopic image).](/cms/asset/52175ff2-afc6-4b42-a141-d6804ed368f5/ianb_a_1241794_f0005_c.jpg)
Figure 6. Effect of aqueous solution of arginine (b), blank nanostructured lipid carrier (NLC) (d) and arginine-loaded NLC (f) on the hair follicles compared with untreated skin (a, c, and e, respectively).
![Figure 6. Effect of aqueous solution of arginine (b), blank nanostructured lipid carrier (NLC) (d) and arginine-loaded NLC (f) on the hair follicles compared with untreated skin (a, c, and e, respectively).](/cms/asset/2a69dc15-51bf-41dc-b816-242d90e6638c/ianb_a_1241794_f0006_c.jpg)
Table 1. The histological effect of arginine-loaded nanostructured lipid carrier (NLC) on hair follicles.