Diagnosing lung cancer using etoposide microparticles labeled with ^99mTc

Figures & data

Table 1. Percentage of labeled etoposide microparticles by ascending chromatograms of ^99mTc compared with free pertechnetate (Na^99mTcO₄⁻) in 2 h.

Time (h)	Labeling (%)±SD
2	99.5 ± 0.4%

Table 2. Percentage of labeled etoposide microparticles by ascending chromatograms of ^99mTc compared with free pertechnetate (Na^99mTcO₄⁻) in 8 h.

Time (h)	Labeling (%)±SD
8	98.9 ± 0.9%

Figure 1. Etoposide microparticle mean size and size distribution.

Figure 2. SEM image. The figure “A” is an immediate image, the “B” is after labeling with ^99mTc and “C” is 1 month after labeling with ^99mTc.

Figure 3. Biodistribution of labeled etoposide microparticles in inducted mice with lung cancer (xenograph model). The y-axis is the dose in μCi and the x-axis is the organ. Is important to observe that lesion means xenograph lung tumor.

Figure 4. SPECT imaging of Balb/c nude mouse inducted with xenograft cancer model in the back.