MicroRNA-133b expression associates with clinicopathological features and prognosis in glioma

Figures & data

Table 1. Clinicopathological characteristics of 97 patients with glioma.

		miR-133b expression level
Characteristics	Cases	Low (n = 48)	High (n = 49)	p value
Age (years)
≥60	57	31	26	.304
<60	40	17	23
Gender
Female	36	20	16	.405
Male	61	28	33
Smoking status
No	39	17	22	.409
Yes	58	31	27
KPS score
≤80	56	37	19	<.001
>80	41	11	30
WHO grade
I–II	51	15	36	<.001
III–IV	46	33	13
Surgery
GTR	53	24	29	.418
PR	44	24	20

KPS score: Karnofsky Performance Scale status score; GTR: gross total resection; PR: partial resection.

Figure 1. qRT-PCR detection of relative miR-133b expression in glioma tissues and normal brain tissues.

Figure 2. Kaplan–Meier curve for overall survival in glioma patients with low versus high miR-133b expression.

Table 2. Multivariate analysis for overall survival in 97 patients with glioma.

Factor	Hazard ratio	95% CI	p value
Age	1.518	0.852–2.192	.173
Gender	0.882	0.533–3.625	.595
Smoking status	2.191	0.895–4.385	.101
KPS score	2.068	1.537–5.993	.009
WHO grade	4.167	2.772–10.926	.003
Surgery	1.528	0.527–3.027	.471
miR-133b level	3.197	1.826–8.055	.017