Figures & data
Figure 1. Schematic representation of preparation of chimeric mice and component of bone marrow cells.
![Figure 1. Schematic representation of preparation of chimeric mice and component of bone marrow cells.](/cms/asset/50bc0c14-0151-4809-b45d-007fd64b1c16/ianb_a_1408118_f0001_c.jpg)
Table 1. Chimera mice groups and vaccination schedule.
Table 2. Serological data of PBMCs donors/patients suffering from hepatitis B virus.
Figure 3. (A) Levels of human immunoglobulins (IgG) and (B) cytokine (IFN-Y) in sera of chimeric mice transplanted with PBMCs of HBV-immunized carriers. Balb/c chimeric mice were transplanted with PBMCs and vaccinated with HBsAg loaded polymeric particles or TT. Sera were collected at day first and 18 days.
![Figure 3. (A) Levels of human immunoglobulins (IgG) and (B) cytokine (IFN-Y) in sera of chimeric mice transplanted with PBMCs of HBV-immunized carriers. Balb/c chimeric mice were transplanted with PBMCs and vaccinated with HBsAg loaded polymeric particles or TT. Sera were collected at day first and 18 days.](/cms/asset/159d56c3-671c-4c50-9706-0b082878150e/ianb_a_1408118_f0003_c.jpg)
Figure 4. (A) HBsAg and (B) Anti-HBs antibody levels in serum of chimeric mice transplanted with PBMCs of HBV-immunized carriers. Balb/c/scid chimeric mice were transplanted with PBMCs and vaccinated the same day with HBsAg loaded polymeric particles. Sera were collected at the indicated time points and assessed.
![Figure 4. (A) HBsAg and (B) Anti-HBs antibody levels in serum of chimeric mice transplanted with PBMCs of HBV-immunized carriers. Balb/c/scid chimeric mice were transplanted with PBMCs and vaccinated the same day with HBsAg loaded polymeric particles. Sera were collected at the indicated time points and assessed.](/cms/asset/56137ed3-3e91-4133-8438-4901af2082f3/ianb_a_1408118_f0004_c.jpg)