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Artificial Cells, Nanomedicine, and Biotechnology
An International Journal
Volume 46, 2018 - Issue sup3
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Research Article

Photodynamic application of protoporphyrin IX as a photosensitizer encapsulated by silica nanoparticles

Ghaseb N. Makhadmeha Al Ghad international College for Medical Sciences, Riyadh, Saudi Arabia;b School of Physics, Universiti Sains Malaysia, Penang, Malaysia;c NanoBiotechnology Research and Innovation (NanoBRI), Institute for Research in Molecular Medicine (INFORMM), Universiti Sains Malaysia, Penang, MalaysiaCorrespondence[email protected]
&
Azlan Abdul Azizb School of Physics, Universiti Sains Malaysia, Penang, Malaysia;c NanoBiotechnology Research and Innovation (NanoBRI), Institute for Research in Molecular Medicine (INFORMM), Universiti Sains Malaysia, Penang, Malaysia
Pages 1043-1046 | Received 06 Aug 2018, Accepted 20 Sep 2018, Published online: 19 Nov 2018

Figures & data

Figure 1. Cytotoxicity on osteosarcoma cells of (a) PpIX-SiNPs, (b) naked PpIX.

Figure 1. Cytotoxicity on osteosarcoma cells of (a) PpIX-SiNPs, (b) naked PpIX.

Figure 2. Cell death percentage for with and without light irradiation: (a) Encapsulated PpIX and (b) Naked PpIX. (c) The ratio of percentage cell death under light irradiation to that of without light irradiation for encapsulated and naked PpIX.

Figure 2. Cell death percentage for with and without light irradiation: (a) Encapsulated PpIX and (b) Naked PpIX. (c) The ratio of percentage cell death under light irradiation to that of without light irradiation for encapsulated and naked PpIX.

Figure 3. Percentage of cell death during exposure to the light of optimal concentration for (a) Encapsulated PpIX and (b) Naked PpIX. (c) The optimum exposure time for encapsulated and naked PpIX.

Figure 3. Percentage of cell death during exposure to the light of optimal concentration for (a) Encapsulated PpIX and (b) Naked PpIX. (c) The optimum exposure time for encapsulated and naked PpIX.

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