Figures & data
Figure 9. miR-3194-3p is down-regulated by hypoxia and mediates the promoting effects of hypoxia on metastasis and EMT of HCC cell. (A) β-catenin protein levels in HCC cells transfected with miR-3194-3p inhibitor or miR-3194-3p over-expression vectors. (B) The expression level of HIF-1α in different time points in hypoxia condition. (C) The expression level of miR-3194-3p in Hep3B cells cultured in normoxia and hypoxia. (D) Transwell assays for Hep3B cells in normoxia and Hep3B cells and Hep3B cells transfected with miR-3194-3p in hypoxia. **p < .01. (E) The expression of BCL9, E-cadherin, N-cadherin and Vimentin of Hep3B cells in normoxia and Hep3B cells and Hep3B cells transfected with miR-3194-3p in hypoxia. *p < .05. n = six independent experiments.
![Figure 9. miR-3194-3p is down-regulated by hypoxia and mediates the promoting effects of hypoxia on metastasis and EMT of HCC cell. (A) β-catenin protein levels in HCC cells transfected with miR-3194-3p inhibitor or miR-3194-3p over-expression vectors. (B) The expression level of HIF-1α in different time points in hypoxia condition. (C) The expression level of miR-3194-3p in Hep3B cells cultured in normoxia and hypoxia. (D) Transwell assays for Hep3B cells in normoxia and Hep3B cells and Hep3B cells transfected with miR-3194-3p in hypoxia. **p < .01. (E) The expression of BCL9, E-cadherin, N-cadherin and Vimentin of Hep3B cells in normoxia and Hep3B cells and Hep3B cells transfected with miR-3194-3p in hypoxia. *p < .05. n = six independent experiments.](/cms/asset/908dc6c3-8f60-4d78-b7da-2133cc6f4efb/ianb_a_1928416_f0001_c.jpg)