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Emerging Microbes & Infections Volume 8, 2019 - Issue 1
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Review Articles

Mycobacterial genomics and structural bioinformatics: opportunities and challenges in drug discovery

Vaishali P. Wamana Department of Biochemistry, University of Cambridge, Cambridge, UKView further author information
,
Sundeep Chaitanya Vedithia Department of Biochemistry, University of Cambridge, Cambridge, UKView further author information
,
Sherine E. Thomasa Department of Biochemistry, University of Cambridge, Cambridge, UKView further author information
,
Bridget P. Bannermana Department of Biochemistry, University of Cambridge, Cambridge, UKView further author information
,
Asma Munira Department of Biochemistry, University of Cambridge, Cambridge, UKView further author information
,
Marcin J. Skwarka Department of Biochemistry, University of Cambridge, Cambridge, UKView further author information
,
Sony Malhotrab Institute of Structural and Molecular Biology, Department of Biological Sciences, Birkbeck College, University of London, London, UKView further author information
&
Tom L. Blundella Department of Biochemistry, University of Cambridge, Cambridge, UKCorrespondence[email protected]
View further author information
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Pages 109-118 | Received 15 Oct 2018, Accepted 09 Dec 2018, Published online: 16 Jan 2019

Figures & data

Figure 1. From mycobacterial genomes to drug discovery. Post-genomic application areas in mycobacterial drug discovery such as comparative genomics and structural biology/bioinformatics are shown.

Figure 1. From mycobacterial genomes to drug discovery. Post-genomic application areas in mycobacterial drug discovery such as comparative genomics and structural biology/bioinformatics are shown.

Figure 2. FBDD cascade. Various techniques involved in each of the four stages are shown.

Figure 2. FBDD cascade. Various techniques involved in each of the four stages are shown.

Related Research Data

Azaaurones as Potent Antimycobacterial Agents Active against MDR- and XDR-TB
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