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Letter

Detectable 2019-nCoV viral RNA in blood is a strong indicator for the further clinical severity

, , , , , , , , , , , , , , , , , , , & show all
Pages 469-473 | Received 08 Feb 2020, Accepted 15 Feb 2020, Published online: 26 Feb 2020

Figures & data

Figure 1. Results of 2019-nCoV viral RNA detection in the blood (A) and anal swab (B). Blood or anal swab positive represents viral RNA positive in at least one test of blood or anal swab samples from the same patient. Blood or anal swab negative represents viral RNA negative in all tests of blood or anal swab samples from the same patient. Severe represents that the patient is diagnosed as a severe symptom after expert consultation while mild represents the rest of the patients. P values are shown (chi-square test, two sides).

Figure 1. Results of 2019-nCoV viral RNA detection in the blood (A) and anal swab (B). Blood or anal swab positive represents viral RNA positive in at least one test of blood or anal swab samples from the same patient. Blood or anal swab negative represents viral RNA negative in all tests of blood or anal swab samples from the same patient. Severe represents that the patient is diagnosed as a severe symptom after expert consultation while mild represents the rest of the patients. P values are shown (chi-square test, two sides).

Figure 2. Diagram of viral detection in patient 1 (A) and 2 (B) with both detectable virus RNA in blood and anal swab. Illness day represents the patients with clear clinical symptoms such as fever, dry-coughing is labelled over the first line. ICU, CDC confirmed, and transfer indicates that the patient is in the ICU ward, CDC confirmation of viral positive, and transfer of patient out from ICU ward to another hospital to receive a higher level of medical care, respectively. Ct value from the pharyngeal, blood and the anal swab is shown.

Figure 2. Diagram of viral detection in patient 1 (A) and 2 (B) with both detectable virus RNA in blood and anal swab. Illness day represents the patients with clear clinical symptoms such as fever, dry-coughing is labelled over the first line. ICU, CDC confirmed, and transfer indicates that the patient is in the ICU ward, CDC confirmation of viral positive, and transfer of patient out from ICU ward to another hospital to receive a higher level of medical care, respectively. Ct value from the pharyngeal, blood and the anal swab is shown.

Figure 3. Diagram of viral detection in Patient 3 (A), 4 (B), 5 (C) and 6 (D) with both detectable virus RNA in blood. Labels are identical to those in . Severe represents that the patient is diagnosed to be severe symptoms (B). Infection day represents the patient with a clear time of infection (D).

Figure 3. Diagram of viral detection in Patient 3 (A), 4 (B), 5 (C) and 6 (D) with both detectable virus RNA in blood. Labels are identical to those in Figure 2. Severe represents that the patient is diagnosed to be severe symptoms (B). Infection day represents the patient with a clear time of infection (D).