Figures & data
Figure 1. Safety and immunogenicity of aerosol Ad5-nCoV. (A) Biodistribution of Ad5-nCoV in the tested organs collected on 31 and 42 DPI. The viral genome in the tissues was assessed with qRT-PCR. (B) Ad5-nCoV presence in the blood at the indicated time points. (C and D) S-specific humoral immune responses in serum and bronchoalveolar lavage. (E and F) Pseudovirus neutralization antibody (PNAb) titres for SARS-CoV-2 WT or Delta variant were elevated in blood and BLA, respectively. ****P < 0.0001, ***P < 0.001.
Supplemental material
