https://orcid.org/0000-0001-9628-4850
Figures & data
Figure 1. (A) Phylogenetic analysis of 11 full-length CV-A4 genomes from the kindergarten outbreak and reference strains available from GenBank. Font colour in the phylogenetic tree represents the collection date of the CV-A4 strains. Maximum likelihood trees in this study were estimated using RAxML (version 8.1.6) [Citation14] under the GTRGAMMA nucleotide substitution model with 1000 bootstrap replicates. The solid red circle represents the Chinese CV-A4 genomes identified by our laboratory, and the open red circle represents the Chinese CV-A4 genomes described by other laboratories. (B) Sequence identity between CV-A4 genomes from the kindergarten outbreak (exemplified by TA001K) and its most closely related strains. Similarity comparison of the potential recombination event in the TA001K genome was performed using Simplot [Citation15], with a window size of 200 bp and a step size of 20 bp. The breakpoints were defined by RDP4 [Citation16].
![Figure 1. (A) Phylogenetic analysis of 11 full-length CV-A4 genomes from the kindergarten outbreak and reference strains available from GenBank. Font colour in the phylogenetic tree represents the collection date of the CV-A4 strains. Maximum likelihood trees in this study were estimated using RAxML (version 8.1.6) [Citation14] under the GTRGAMMA nucleotide substitution model with 1000 bootstrap replicates. The solid red circle represents the Chinese CV-A4 genomes identified by our laboratory, and the open red circle represents the Chinese CV-A4 genomes described by other laboratories. (B) Sequence identity between CV-A4 genomes from the kindergarten outbreak (exemplified by TA001K) and its most closely related strains. Similarity comparison of the potential recombination event in the TA001K genome was performed using Simplot [Citation15], with a window size of 200 bp and a step size of 20 bp. The breakpoints were defined by RDP4 [Citation16].](/cms/asset/135a5d97-4299-4522-b642-06a7af51dafa/temi_a_2114855_f0001_oc.jpg)
