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Review

Clostridioides difficile spore: coat assembly and formation

ORCID Icon, , ORCID Icon & ORCID Icon
Pages 2340-2349 | Received 16 Jun 2022, Accepted 25 Aug 2022, Published online: 29 Sep 2022

Figures & data

Figure 1. Sporulation of Clostridioides difficile. This figure summarizes the sporulation initiation and spore formation described in this review. Red arrows indicate transcriptional activation. Red cross arrows indicate transcriptional inhibition. Red bold arrows indicate post-translational regulations. Question marks indicate suggestive but unconfirmed mechanisms.

Figure 1. Sporulation of Clostridioides difficile. This figure summarizes the sporulation initiation and spore formation described in this review. Red arrows indicate transcriptional activation. Red cross arrows indicate transcriptional inhibition. Red bold arrows indicate post-translational regulations. Question marks indicate suggestive but unconfirmed mechanisms.

Figure 2. Coat assembly of Clostridioides difficile. This figure summarizes the coat assembly process described in this review. The coloured boxes on the left indicate SigE and SigK regulon. The box on the top right shows a proposed model of the spore coat assembly of the first stage, while the box on the bottom right shows the second stage. Question marks indicate unknown/unconfirmed proteins.

Figure 2. Coat assembly of Clostridioides difficile. This figure summarizes the coat assembly process described in this review. The coloured boxes on the left indicate SigE and SigK regulon. The box on the top right shows a proposed model of the spore coat assembly of the first stage, while the box on the bottom right shows the second stage. Question marks indicate unknown/unconfirmed proteins.