Figures & data
Figure 1. Clinical features and IL-17RC mutations in the present case. A. Tongue dorsum displayed deep fissures with unclear-bordered nodular hyperplasia, along with thickened white plaques with a granular surface on the stiffened dorsum and the lateral border. B. The patient had no typical cutaneous manifestations except for an erythematous plaque with adherent scaling on the antihelix. C. Histopathological examination of the lingual mucosa biopsy specimens revealed superficial mucosal hyperparakeratosis, inflammatory cell infiltration, and microabscess formation (magnification: ×100). D. The periodic acid–Schiff staining demonstrated fungal hyphae traversing perpendicularly through the surface epithelium up to the spinous cell layer (magnification: ×200). E. Sanger sequencing of the IL-17RC gene in family members of the patient: *arrows indicate the mutation sites.
