Elevated colorectal cancer incidence among American Indian/Alaska Native persons in Alaska compared to other populations worldwide

Figures & data

Figure 1. Map of United States Indian health service regions.

Table 1. Age-adjusted colorectal cancer incidence rates,^a counts, and population for American Indian/Alaska Native persons, by United States region, all counties, 2018.

Region		Rate	SE	Lower CI	Upper CI	Count	Population
Alaska	Male and female	61.9	7.0	49.0	77.2	81	128,287
Alaska	Male	63.6	10.2	45.2	87.0	40	64,917
Alaska	Female	59.8	9.5	42.6	81.6	41	63,370
Southern Plains	Male and female	31.1	1.9	27.4	35.1	265	789,140
Southern Plains	Male	36.0	3.0	30.3	42.4	145	396,146
Southern Plains	Female	26.9	2.5	22.3	32.3	120	392,994
Northern Plains	Male and female	22.9	1.9	19.4	27.0	148	654,135
Northern Plains	Male	27.6	3.1	21.9	34.3	84	326,219
Northern Plains	Female	19.0	2.4	14.6	24.3	64	327,916
Southwest	Male and female	18.2	1.5	15.4	21.3	152	813,988
Southwest	Male	19.1	2.3	14.9	24.0	72	401,544
Southwest	Female	17.4	2.0	13.8	21.7	80	412,444
Pacific Coast	Male and female	15.0	1.2	12.8	17.5	172	1,082,582
Pacific Coast	Male	15.9	1.7	12.7	19.7	85	546,143
Pacific Coast	Female	14.4	1.6	11.6	17.9	87	536,439
East	Male and female	11.3	0.9	9.7	13.2	166	1,208,075
East	Male	11.8	1.3	9.4	14.7	84	609,562
East	Female	10.9	1.2	8.7	13.6	82	598,513
All regions	Male and female	19.3	0.6	18.1	20.5	984	4,676,207
All regions	Male	21.2	0.9	19.4	23.2	510	2,344,531
All regions	Female	17.7	0.8	16.1	19.4	474	2,331,676

^aAll data age-adjusted using the World Health Organization’s World Standard Population (2000–2025).

Table 2. Age-adjusted colorectal cancer incidence rates, counts, and population by race, Alaska, 2014–2018.

Sex	Race^a	Rate^b	Lower CI	Upper CI	Count	Population
Male and female	All races	31.3	29.6	32.9	1,462	3,690,076
Male and female	White	26.4	24.7	28.2	942	2,567,692
Male and female	Black	17.1	10.7	25.7	24	178,375
Male and female	AI/AN	67.1	60.8	73.9	420	636,660
Male and female	API	20.3	15.8	25.7	71	307,349
Male	All races	33.5	31.2	36	803	1,929,578
Male	White	29.5	27	32.1	552	1,359,708
Male	Black	19.9	10.2	34.5	14	98,791
Male	AI/AN	67.2	58.1	77.3	200	322,706
Male	API	23.0	15.8	32.5	34	148,373
Female	All races	28.9	26.7	31.2	659	1,760,498
Female	White	23.1	20.8	25.6	390	1,207,984
Female	Black	14.4	6.8	26.5	10	79,584
Female	AI/AN	66.7	58.1	76.2	220	313,954
Female	API	19.0	13.3	26.3	37	158,976

^aAll rates per 100,000 and age-adjusted using the World Health Organization’s World Standard Population (2000–2025).

^bNon-Hispanic and Hispanic included.

AI/AN = American Indian/Alaska Native; API = Asian or Pacific Islander

Figure 2. Trends in colorectal cancer incidence rates, American Indian/Alaska Native (AI/AN) persons and White persons, Alaska, 1999–2018.

Table 3. Top 10 colorectal cancer incidence rates worldwide, by men and women, 2018*.

Rank	Country	Age-standardised rate per 100,000
Men and Women, combined
1	Hungary	51.2
2	South Korea	44.5
3	Slovakia	43.8
4	Norway	42.9
5	Slovenia	41.1
6	Denmark	41.0
6	Portugal	40.0
8 =	Barbados	38.9
8 =	Japan	38.9
10	Netherlands	37.8
Women
1	Norway	39.3
2	Hungary	36.8
3	Denmark	36.6
4	Singapore	34.0
5	Australia	32.4
6	South Korea	31.3
7	Slovakia	31.2
8	Netherlands	31.1
9	New Zealand	30.8
10	Japan	29.6
Men
1	Hungary	70.6
2	Slovakia	60.7
3	South Korea	59.5
4	Slovenia	58.9
5	Portugal	54.0
6	Barbados	50.3
7	Japan	49.1
8	Serbia	49.0
9	Moldova	47.3
10	Norway	46.9

*Data source: World Health Organization/International Agency for Research on Cancer, Global Cancer Observatory, GLOBOCAN 2018 database (https://gco.iarc.fr).