HIV transmission in twin pregnancy: Maternal and perinatal outcomes

Figures & data

Table 1: Demographic and clinical data of HIV uninfected and HIV infected women with twin pregnancies

Variable	Total (n = 186)	HIV negative (n = 106)	HIV positive (n = 80)	p value
Age (years)	28.3 ± 7.0 (15-48)	27.07 ± 7.3	30.0 ± 6.3	<0.004
Parity	1 ± 1 (0-7)	1.2 ± 1.4	1.6 ± 1.2	<0.03
Gravidity	1 ± 1 (1-8)	2.3 ± 1.5	2.6 ± 1.2	0.17
Antenatal care visits	6.07 ± 2.68 (1-15)	5.9 ± 2.7	6.3 ± 2.7	0.41
Blood pressure (mmHg):
Systolic	115.14 ± 15.07	115.9±15.5	114.5±14.6	0.3
Diastolic	68.81 ± 9.8	68.9±10.1	68.7±9.5	0.9
Gestational age @ delivery (weeks)	34.8± 4.5	34.7±3.5	34.6±3.6	0.78

Table 2: Obstetric complications in HIV uninfected and HIV infected women with twin deliveries

Complications	Number (%)	HIV-ve (n = 106)	HIV+ve (n = 80)	p value
Preterm labour	63 (33.9)	29 (27.4)	34 (42.5)	0.03
Anaemia^*	7 (3.8)	0 (0)	7 (8.8)	0.003
Abruptio placentae	4 (2.2)	3 (2.8)	1 (1.3)	0.4
Hypertensive disorders of pregnancy	45 (24.2)	32(30.2)	13 (16.3)	0.02
Pre-eclampsia	26 (57.2)	19 (73.1)	7 (26.9)
Gestational hypertension	8 (17.8)	6 (75)	2 (25)
Severe pre-eclampsia	11 (24.4)	7 (63.6)	4 (36.4)

^* 3 cases of severe anaemia in the HIV infected group was ART (zidovudine) related.

Anaemia (<10 g/dL) was present in 42.5% (n = 34) of patients.