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Research Article

Chemoprotection by Kolaviron of Garcinia kola in Benzene-induced leukemogenesis in Wistar rats

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Pages 151-161 | Received 21 Sep 2021, Accepted 26 Feb 2022, Published online: 29 Mar 2022

Figures & data

Figure 1. Photomicrograph of peripheral blood smear of representative leukemic rats showing the presence of blast (black arrow) and poikilocytosis (blue arrow).

Figure 1. Photomicrograph of peripheral blood smear of representative leukemic rats showing the presence of blast (black arrow) and poikilocytosis (blue arrow).

Table 1. Effect of kolaviron on hematological parameters and blood morphology of benzene-induced leukemia in rats

Figure 2. Photomicrograph showing the Influence of kolaviron on bone marrow architecture of benzene-induced leukemia in wistar rats.

Figure 2. Photomicrograph showing the Influence of kolaviron on bone marrow architecture of benzene-induced leukemia in wistar rats.

Figure 3. Effect of kolaviron on formation of micronucleated polychromatic erythrocytes (mPCEs) in benzene-induced leukemia in wistar rats.

Data are expressed as mean ±S.D for six rats in each group *significantly different from the control p < 0.05# significantly different from the LKM group
Figure 3. Effect of kolaviron on formation of micronucleated polychromatic erythrocytes (mPCEs) in benzene-induced leukemia in wistar rats.

Figure 4. Effect of kolaviron on plasma oxidative stress markers: Advanced Oxidation Protein Products—AOPPs (A), total thiol (B) and plasma activity of arylesterase (C) on benzene-induced leukemia in Wistar rats.

Data are expressed as mean ±S.D for six rats in each group *significantly different from the control p < 0.05# significantly different from the LKM group
Figure 4. Effect of kolaviron on plasma oxidative stress markers: Advanced Oxidation Protein Products—AOPPs (A), total thiol (B) and plasma activity of arylesterase (C) on benzene-induced leukemia in Wistar rats.