A Cluster Analysis of Pediatric Cancer Incidence Rates in Florida: 2000–2010

Figures & data

Figure 1. Cluster analysis of Brain/CNS incidence rates (adjusted for age and sex) for 2000–2010 in Florida.

Figure 2. Age and sex-adjusted brain tumor rates in Florida (out of 100,000).

Figure 3. Cluster analysis of leukemia incidence rates (adjusted for age and sex) for 2000–2010 in Florida.

Figure 4. Age and sex-adjusted leukemia rates in Florida (out of 100,000).

Figure 5. Cluster analysis of lymphoma incidence rates (adjusted for age and sex) for 2000–2010 in Florida.

Figure 6. Age and sex adjusted lymphoma rates in Florida (out of 100,000).

Table 1. Univariate purely spatial cluster analysis of age and sex-adjusted incidence rates

Cancer type	Relative risk	Number of cases	Expected number of cases	p-value
Brain	1.34	409	334.77	0.012
Leukemia	1.35	279	215.31	0.029
Lymphoma	1.52	160	113.68	0.024
All Cancers	1.29	1264	1022.17	<0.00001

Table 2. Cancer rate estimates (out of 100,000) and standard deviations (mean, SDV)

	Brain	Leukemia	Lymphoma	All cancers
Cluster	3.03, 0.54	4.98, 0.99	2.17, 0.33	16.92, 2.46
Outside Cluster	2.27, 0.16	3.68, 0.42	1.42, 0.16	13.07, 0.87
Florida	2.48, 0.22	3.83, 0.41	1.54,.15	13.67, 0.94

Table 3. Multivariate cluster for age and sex adjusted cancer rates (p = 0.0038)

Cancer type	Relative risk	Number of cancer cases	Expected number of cancer cases
Brain	1.03	151	146.56
Leukemia	1.31	283	224.41
Lymphoma	1.46	126	91.17

Figure 7. Multivariate cluster analysis of (brain, leukemia, lymphoma) incidence rates (adjusted for age and sex) for 2000–2010 in Florida.

Figure 8. Age and sex adjusted total cancer rates in Florida (out of 100,000)

Figure 9. Cluster analysis of all pediatric cancer types (adjusted for age and sex) for 2000–2010 in Florida with a spatial poisson model.