Acute and chronic toxicities assessment of arsenic (III) to catfish, Silurus lanzhouensis in China

Figures & data

Table 1. LC₅₀ of arsenic in Lanzhou catfish at selected time intervals

Time (h)	LC50 (mg/L)	STD	r^2
24	31.72	0.55	0.91
48	20.89	−0.62	0.87
72	13.28	−0.2	0.97
96	12.88	0.28	0.93
120	12.23	0.23	0.95
144	11.54	0.24	0.93

Note: Values obtained using a trimmed Spearman–Karber method with 95% confidence.

Figure 1. Changes in As concentrations in the brain, gill, liver, and muscle during the exposure phase and recovery phase. Values represent the mean S.E. of triplicate subsamples. Values at a given time that are significantly different are indicated by different letters (p < 0.05).

Table 2. Kinetic parameters of arsenic for Lanzhou catfish

Organ	Treats	k1 (mL/g d)	k2 (d^−1)	BCF (mL/g)	CAmax(mg/㎏)	t1/2 (d)
Gill	T1	0.1473	0.2105	0.70	0.90	3.3
	T2	0.0723	0.0943	0.77	0.38	7.3
	T3	0.0219	0.0276	0.79	0.08	25.1
Muscle	T1	0.0612	0.0952	0.64	0.83	7.3
	T2	0.0536	0.0831	0.65	0.32	8.3
	T3	0.0175	0.0263	0.67	0.07	26.4
Brain	T1	0.0426	0.0781	0.55	0.70	8.9
	T2	0.0156	0.0270	0.58	0.29	25.7
	T3	0.0099	0.0164	0.60	0.06	42.3
Liver	T1	0.0054	0.0304	0.18	0.23	22.8
	T2	0.0042	0.0197	0.21	0.11	35.2
	T3	0.0012	0.0061	0.20	0.02	113.6

Figure 2. Optimal fit of the AUC-based TIC acute toxicity model to the LC50(t) data (mean ± 95% confidence interval) listed in Table 2.

Figure 3. Predicted internal effect concentration–time response relationships in target organs of Lanzhou catfish when exposed to 1.288 mg/L waterborne arsenic, at the site of action that causes 50% mortality.