The effects of oral calcium on the prevention of moderate to severe ovarian hyperstimulation syndrome in high-risk patients: A placebo-controlled study

Figures & data

Table 1. A comparison of the demographic status of the patients between two groups

Variable	Calcium group mean±SD	Placebo group mean±SD	P Value
Age	32.42 ± 5.20	30.10 ± 6.08	0.27
BMI	26.18 ± 4.01	25.86 ± 4.27	0.86
AMH	7.91 ± 7.61	5.90 ± 4.78	0.53
Duration of infertility(years)	4.68 ± 2.70	5.77 ± 5.93	0.53
Serum estradiol level pg/ml	3047.10 ± 760.86	3067.27 ± 762.11	0.94

Table 2. The causes of infertility between two groups

Variables	Calcium group	Placebo group	P Value
Male factor	7%	37%	0.07
Tubal	7%	12%	0.67
Unexplained	7%	0%	0.43
Endometriosis	14%	25%	0.53
PCO	71%	37%	0.11
Metformin consumption	47%	18%	0.10

Figure 1. A comparison of oocyte count and embryo transfer rate between calcium and placebo groups.

Figure 2. A comparison of clinical pregnancy between calcium and placebo groups.

Table 3. A comparison of the oocyte count and embryo grading and clinical pregnancy between calcium and placebo groups

Variables	Calcium group mean±SD	Placebo group Mean±SD	P Value
Oocyte count	13.33 ± 6.08	14.09 ± 2.46	0.62
Embryo count	9.43 ± 5.98	10.00 ± 1.85	0.73
Embryo grade A	8.00 ± 5.57	7.37 ± 4.53	0.78
Embryo grade B	0.37 ± 0.80	1.50 ± 3.50	0.39
Embryo grade C	1.00 ± 1.89	1.25 ± 1.58	0.75

Table 4. A comparison of clinical pregnancy and embryo transfer rate between calcium and placebo groups

Variables	Calcium group	Placebo group	P Value
Embryo transfer rate	28%	63%	0.055
Clinical pregnancy	33%	28%	0.85

Table 5. A comparison some symptoms of OHSS and Prevalence of mild, moderate and sever OHSS between two groups

Variables	Calcium group	Placebo group	P Value
Nausea	14%	0%	0.18
Abdominal pain	42%	36%	0.72
Mild abdominal pain	19%	9%	0.46
Moderate abdominal pain	9%	27%	0.18
Severe abdominal pain	4%	0%	0.46
Distention	4%	0%	0.46
Mild fluid	28%	18%	0.51
Moderate fluid	52%	54%	0.90
Severe fluid	4%	0%	0.46
Mild OHSS	38%	45%	0.68
Moderate OHSS	57%	54%	0.88
Severe OHSS	4%	0%	0.46

Figure 3. A comparison some symptoms of OHSS and Prevalence of mild, moderate and sever OHSS between two groups.

Table 6. A comparison between mean of blood WBC and Hb and HCT between two groups

Variables	Calcium group mean±SD	Placebo group mean±SD	P Value
WBC	10,442.85 ± 2940.84	9188.18 ± 2261.79	0.22
Hb	12.12 ± 1.22	13.00 ± 1.18	0.06
Hct	39.00 ± 3.19	40.36 ± 3.10	0.25