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Legacy

Osamu Hayaishi—from the discovery of oxygenases in soil microorganisms to unraveling the enigma of sleep in mammals

, &
Pages 303-307 | Received 07 Jul 2015, Accepted 08 Jul 2015, Published online: 15 Oct 2015

Figures & data

Figure 1. Osamu Hayaishi (left) and Yoshihiro Urade (right) at the library of Osaka Bioscience Institute (OBI), ca. 2005. Osamu Hayaishi was director of OBI from 1993–1998 and also served as the head of the Department of Molecular Behavioral Biology, which focused on elucidating the molecular mechanisms of sleep/wake regulation. In 1998, Yoshihiro Urade assumed the position of Department Head from Hayaishi who concentrated on being Director of OBI. Photo Credit: Yoshihiro Urade, Japan.

Figure 1. Osamu Hayaishi (left) and Yoshihiro Urade (right) at the library of Osaka Bioscience Institute (OBI), ca. 2005. Osamu Hayaishi was director of OBI from 1993–1998 and also served as the head of the Department of Molecular Behavioral Biology, which focused on elucidating the molecular mechanisms of sleep/wake regulation. In 1998, Yoshihiro Urade assumed the position of Department Head from Hayaishi who concentrated on being Director of OBI. Photo Credit: Yoshihiro Urade, Japan.

Figure 2. Osamu Hayaishi, Clifford Saper, Zhi-Li Huang and Michael Lazarus at Osaka Bioscience Institute (OBI; left to right), ca. 2007. Clifford Saper (from Harvard Medical School) was a speaker at OBI's Monthly Lecture series on several occasions and was a member of OBI's Board of Advisors from 2010–2013. Osamu Hayaishi is a great admirer of Professor Saper's work on the hypothalamic regulation of body temperature, sleep and circadian rhythms.Citation32,33 Photo Credit: Michael Lazarus, Japan.

Figure 2. Osamu Hayaishi, Clifford Saper, Zhi-Li Huang and Michael Lazarus at Osaka Bioscience Institute (OBI; left to right), ca. 2007. Clifford Saper (from Harvard Medical School) was a speaker at OBI's Monthly Lecture series on several occasions and was a member of OBI's Board of Advisors from 2010–2013. Osamu Hayaishi is a great admirer of Professor Saper's work on the hypothalamic regulation of body temperature, sleep and circadian rhythms.Citation32,33 Photo Credit: Michael Lazarus, Japan.

Figure 3. Osamu Hayaishi was the driving force for the Osaka Bioscience Institute (operated between 1987 and 2015), simply known as OBI, to become a world leading center of scientific research. The unique and elegant building of OBI with metallic external walls (upper photo) was designed by the late Kenzo Tange, perhaps the most famous architect from Japan. At the entrance to OBI stands a sculpture entitled “La Porte d'Espérance” in French, meaning “Gate of Hope” in English. It is a masterpiece by the late Yasuo Mizui, an internationally renowned Japanese sculptor. The lower photo shows members of the Department of Molecular Behavioral Biology, also known as the “2nd Department,” which includes Director Emeritus Osamu Hayaishi (center), Head Yoshihiro Urade (right) and Staff Scientist Michael Lazarus (upper left), in the marble entrance hall of OBI, ca. 2010. Photo Credit: Yoshihiro Urade and Yoan Chérasse, Japan.

Figure 3. Osamu Hayaishi was the driving force for the Osaka Bioscience Institute (operated between 1987 and 2015), simply known as OBI, to become a world leading center of scientific research. The unique and elegant building of OBI with metallic external walls (upper photo) was designed by the late Kenzo Tange, perhaps the most famous architect from Japan. At the entrance to OBI stands a sculpture entitled “La Porte d'Espérance” in French, meaning “Gate of Hope” in English. It is a masterpiece by the late Yasuo Mizui, an internationally renowned Japanese sculptor. The lower photo shows members of the Department of Molecular Behavioral Biology, also known as the “2nd Department,” which includes Director Emeritus Osamu Hayaishi (center), Head Yoshihiro Urade (right) and Staff Scientist Michael Lazarus (upper left), in the marble entrance hall of OBI, ca. 2010. Photo Credit: Yoshihiro Urade and Yoan Chérasse, Japan.