Assessing the risk of acute kidney injury following exercise in the heat: Timing is important

Figures & data

Figure 1. Illustrative model depicting the importance of the timing of when biological samples are collected for assessment of acute kidney injury biomarkers following exercise in the heat. Panel A shows a hypothetical kinetic response of acute kidney injury biomarkers based on data from our previous study in response to exercise in the heat without sample collection during a recovery period. Panel B is the same situation but includes biological sample collection during a recovery period. By contrasting Panel A with Panel B, it can be observed that the conclusions drawn regarding the influence of exercise in the heat on acute kidney injury biomarkers differ depending on when biological samples are obtained. This figure is not drawn to scale, but the illustration is modeled from data presented in Chapman et al. [4]

Chapman CL, Johnson BD, Vargas NT, et al. Hyperthermia and dehydration during physical work in the heat both contribute to the risk of acute kidney injury. J Appl Physiol. 2020. DOI:10.1152/japplphysiol.00787.2019

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